HitPredict

Interactor 1: ARI1A (O14497)
AT-rich interactive domain-containing protein 1A (ARID domain-containing protein 1A) (B120) (BRG1-associated factor 250) (BAF250) (BRG1-associated factor 250a) (BAF250A) (Osa homolog 1) (hOSA1) (SWI-like protein) (SWI/SNF complex protein p270) (SWI/SNF-related, matrix-associated, actin-dependent regulator of chromatin subfamily F member 1) (hELD)
Gene: ARID1A

Interactor 2: RARA (P10276)
Retinoic acid receptor alpha (RAR-alpha) (Nuclear receptor subfamily 1 group B member 1)
Gene: RARA

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.60	0.501

Property	Details
Experiments	17363140
Identification Methods	pull down
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000785 - chromatin GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0045893 - positive regulation of DNA-templated transcription
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 2285 Hs			1 462
+	Hs
		146142 ARI1A_HUMAN (11-2285): 0: 871: 100.00		RARB_HUMAN (1-462): 6.17e-151: 438: 77.75
+	Mm
		57758 ARI1A_MOUSE (18-2285): 0: 866: 94.63		RARA_MOUSE (1-462): 2.98e-150: 437: 98.27
+	Hs
		146150 ARI1A_HUMAN (11-2285): 0: 871: 100.00		RARG_HUMAN (1-448): 9.31e-131: 387: 71.62
+	Hs
		146131 ARI1A_HUMAN (11-2285): 0: 871: 100.00		ESR1_HUMAN (5-460): 2.32e-119: 362: 21.81
+	Hs
		146172 ARI1A_HUMAN (11-2285): 0: 871: 100.00		HNF4A_HUMAN (61-462): 6.66e-120: 360: 24.52
+	Mm
		57773 ARI1A_MOUSE (18-2285): 0: 866: 94.63		ERR2_MOUSE (5-417): 5.86e-110: 333: 27.05
+	Hs
		370715 MACF1_HUMAN (1693-1935): 6.32e-57: 222: 12.73		ESR1_HUMAN (5-460): 2.32e-119: 362: 21.81
+	Hs
		1269937 MACF1_HUMAN (1693-1935): 6.32e-57: 222: 12.73		ESR2_HUMAN (3-447): 3.53e-106: 327: 24.89
+	Hs
		782641 ARI3A_HUMAN (833-1199): 9.78e-47: 181: 23.94		HNF4A_HUMAN (61-462): 6.66e-120: 360: 24.52
+	Hs
		782590 ARI3B_HUMAN (924-1202): 8.52e-46: 177: 23.16		HNF4A_HUMAN (61-462): 6.66e-120: 360: 24.52
+	Hs
		1269453 ARI3A_HUMAN (833-1199): 9.78e-47: 181: 23.94		ESR2_HUMAN (3-447): 3.53e-106: 327: 24.89
+	Hs
		368927 MUC1_HUMAN (3-682): 2.67e-34: 146: 12.21		ESR1_HUMAN (5-460): 2.32e-119: 362: 21.81
+	Hs
		554279 MUC1_HUMAN (3-682): 2.67e-34: 146: 12.21		PPARG_HUMAN (66-416): 9.52e-115: 348: 30.26
+	Hs
		554348 MUC1_HUMAN (3-682): 2.67e-34: 146: 12.21		ESR2_HUMAN (3-447): 3.53e-106: 327: 24.89
+	Hs
		782532 BPTF_HUMAN (253-605): 5.59e-15: 83.8: 22.56		HNF4A_HUMAN (61-462): 6.66e-120: 360: 24.52
+	Dm
		558435 Q86BH2_DROME (690-1614): 7.53e-13: 76.8: 9.71		7UP1_DROME (27-423): 3.1e-116: 353: 25.00
+	Hs
		1270066 PCLO_HUMAN (1-1085): 1.56e-17: 92.3: 7.99		ESR2_HUMAN (3-447): 3.53e-106: 327: 24.89
+	Hs
		1017331 BPTF_HUMAN (253-605): 5.59e-15: 83.8: 22.56		ESR2_HUMAN (3-447): 3.53e-106: 327: 24.89
+	Mm
		101828 F8WI37_MOUSE (861-1717): 8.54e-13: 76.8: 11.87		ERR2_MOUSE (5-417): 5.86e-110: 333: 27.05
+	Mm
		1142676 KMT2C_MOUSE (861-1717): 8.26e-13: 76.8: 11.87		ERR2_MOUSE (5-417): 5.86e-110: 333: 27.05