HitPredict

Interactor 1: ARI1A (O14497)
AT-rich interactive domain-containing protein 1A (ARID domain-containing protein 1A) (B120) (BRG1-associated factor 250) (BAF250) (BRG1-associated factor 250a) (BAF250A) (Osa homolog 1) (hOSA1) (SWI-like protein) (SWI/SNF complex protein p270) (SWI/SNF-related, matrix-associated, actin-dependent regulator of chromatin subfamily F member 1) (hELD)
Gene: ARID1A

Interactor 2: SMAD2 (Q15796)
Mothers against decapentaplegic homolog 2 (MAD homolog 2) (Mothers against DPP homolog 2) (JV18-1) (Mad-related protein 2) (hMAD-2) (SMAD family member 2) (SMAD 2) (Smad2) (hSMAD2)
Gene: SMAD2

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	18003620
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000785 - chromatin GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0045893 - positive regulation of DNA-templated transcription
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 2285 Hs			1 467
+	Hs
		146196 ARI1A_HUMAN (11-2285): 0: 871: 100.00		SMAD3_HUMAN (1-467): 0: 617: 83.94
+	Mm
		57764 ARI1A_MOUSE (18-2285): 0: 866: 94.63		SMAD1_MOUSE (1-467): 0: 566: 55.42
+	Hs
		1017303 BPTF_HUMAN (253-605): 5.59e-15: 83.8: 22.56		SMAD2_HUMAN (1-467): 0: 675: 100.00
+	Mm
		503177 CO1A1_MOUSE (969-1670): 1.01e-12: 76.1: 9.58		SMAD2_MOUSE (1-467): 0: 675: 99.57
+	Hs
		358519 CO1A1_HUMAN (975-1691): 8.46e-12: 73.4: 9.33		SMAD2_HUMAN (1-467): 0: 675: 100.00
+	Hs
		1078592 ARI1B_HUMAN (515-1635): 3.77e-10: 68: 8.52		SMAD2_HUMAN (1-467): 0: 675: 100.00
+	Hs
		1078590 KMT2C_HUMAN (558-1643): 1.18e-09: 66.3: 13.57		SMAD2_HUMAN (1-467): 0: 675: 100.00
+	Hs
		1057763 NCOA6_HUMAN (7-957): 6.25e-09: 63.8: 8.91		SMAD2_HUMAN (1-467): 0: 675: 100.00
+	Hs
		950158 BPTF_HUMAN (253-605): 5.59e-15: 83.8: 22.56		SMAD3_HUMAN (1-467): 0: 617: 83.94
+	Mm
		503178 CO1A1_MOUSE (969-1670): 1.01e-12: 76.1: 9.58		SMAD3_MOUSE (1-467): 0: 617: 83.94
+	Hs
		358494 CO1A1_HUMAN (975-1691): 8.46e-12: 73.4: 9.33		SMAD3_HUMAN (1-467): 0: 617: 83.94
+	Hs
		950184 NCOA6_HUMAN (7-957): 6.25e-09: 63.8: 8.91		SMAD3_HUMAN (1-467): 0: 617: 83.94
+	Hs
		171421 ARI1B_HUMAN (515-1635): 3.77e-10: 68: 8.52		SMAD9_HUMAN (1-467): 0: 564: 54.56
+	Hs
		1057764 NCOA6_HUMAN (7-957): 6.25e-09: 63.8: 8.91		SMAD1_HUMAN (1-467): 0: 565: 55.53
+	Mm
		503173 CO1A1_MOUSE (969-1670): 1.01e-12: 76.1: 9.58		SMAD4_MOUSE (11-456): 1.37e-150: 441: 31.46
+	Hs
		358510 CO1A1_HUMAN (975-1691): 8.46e-12: 73.4: 9.33		SMAD4_HUMAN (11-456): 4.53e-151: 443: 31.58
+	Mm
		192481 CO1A1_MOUSE (969-1670): 1.01e-12: 76.1: 9.58		SMAD7_MOUSE (13-443): 5.17e-112: 338: 25.00