HitPredict

Interactor 1: ISLR (O14498)
Immunoglobulin superfamily containing leucine-rich repeat protein
Gene: ISLR

Interactor 2: RHBT3 (O94955)
Rho-related BTB domain-containing protein 3 (EC 3.6.1.-)
Gene: RHOBTB3

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.74	0.60	0.667

Property	Details
Experiments	26186194, 28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0070062 - extracellular exosome
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 428 Hs			1 611
+	Hs
		49981 PXDNL_HUMAN (200-387): 7.46e-14: 76: 12.11		RHBT1_HUMAN (31-611): 3.3e-116: 363: 18.45
+	Hs
		894171 AMGO2_HUMAN (6-347): 5e-41: 154: 22.28		CDC42_HUMAN (31-209): 2.37e-74: 237: 18.85
+	Hs
		925398 AMGO2_HUMAN (6-347): 5e-41: 154: 22.28		RAC1_HUMAN (31-206): 5.82e-66: 215: 20.75
+	Hs
		892456 AMGO2_HUMAN (6-347): 5e-41: 154: 22.28		RAC3_HUMAN (31-196): 1.39e-65: 214: 19.10
+	Hs
		545469 AMGO2_HUMAN (6-347): 5e-41: 154: 22.28		RAC2_HUMAN (31-205): 2.83e-64: 211: 19.25
+	Hs
		894276 PXDN_HUMAN (236-387): 1.99e-16: 84.1: 14.94		CDC42_HUMAN (31-209): 2.37e-74: 237: 18.85
+	Hs
		925580 LGR4_HUMAN (19-176): 4.6e-21: 97.8: 37.34		RAC1_HUMAN (31-206): 5.82e-66: 215: 20.75
+	Hs
		892569 LGR4_HUMAN (19-176): 4.6e-21: 97.8: 37.34		RAC3_HUMAN (31-196): 1.39e-65: 214: 19.10
+	Hs
		900857 LGR4_HUMAN (19-176): 4.6e-21: 97.8: 37.34		RHOA_HUMAN (29-204): 6.83e-65: 213: 17.55