HitPredict

Interactor 1: ISLR (O14498)
Immunoglobulin superfamily containing leucine-rich repeat protein
Gene: ISLR

Interactor 2: S11IP (Q8N1F8)
Serine/threonine-protein kinase 11-interacting protein (LKB1-interacting protein 1)
Gene: STK11IP

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.611

Property	Details
Experiments	26186194, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005576 - extracellular region
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 428 Hs			1 1088
+	Hs
		1185463 LIGO2_HUMAN (8-418): 2.47e-31: 128: 16.55		S11IP_HUMAN (1-1088): 0: 1106: 100.00
+	Hs
		146395 ISLR_HUMAN (18-404): 3.69e-66: 219: 100.00		LRRC1_HUMAN (51-394): 1.31e-38: 153: 19.36
+	At
		1325020 PXL1_ARATH (30-317): 4.35e-23: 104: 15.02		PXL1_ARATH (6-466): 4.71e-59: 223: 15.58
+	Mm
		1193424 LRC4C_MOUSE (3-409): 4.24e-56: 197: 17.66		LRRC7_MOUSE (167-544): 2.53e-25: 116: 14.75
+	Hs
		146404 ISLR_HUMAN (18-404): 3.69e-66: 219: 100.00		LRC40_HUMAN (165-308): 1.25e-11: 70.9: 25.83
+	Mm
		1193434 LRC4C_MOUSE (3-409): 4.24e-56: 197: 17.66		ERBIN_MOUSE (12-197): 6.92e-18: 91.8: 17.74
+	At
		186955 BRI1_ARATH (11-320): 3.49e-18: 89.1: 13.03		BAME3_ARATH (50-614): 1.27e-46: 183: 14.55
+	Hs
		1050047 LGR4_HUMAN (19-176): 4.6e-21: 97.8: 37.34		SCRIB_HUMAN (1-174): 1.23e-15: 84.4: 14.50
+	Hs
		1050029 LRIG1_HUMAN (33-317): 1.32e-20: 96.8: 17.63		SCRIB_HUMAN (1-174): 1.23e-15: 84.4: 14.50
+	Hs
		1315142 LGR4_HUMAN (19-176): 4.6e-21: 97.8: 37.34		LGR4_HUMAN (98-296): 3.23e-13: 76.3: 27.18
+	At
		1114706 PXL1_ARATH (30-317): 4.35e-23: 104: 15.02		ERECT_ARATH (255-502): 5.38e-11: 69: 12.80
+	Hs
		1315173 LGR4_HUMAN (19-176): 4.6e-21: 97.8: 37.34		NISCH_HUMAN (3-145): 2.91e-12: 73.3: 14.77
+	Hs
		1295422 LGR4_HUMAN (19-176): 4.6e-21: 97.8: 37.34		LRIQ1_HUMAN (156-346): 7.33e-12: 72.1: 25.12
+	Hs
		1294956 LRIG1_HUMAN (33-317): 1.32e-20: 96.8: 17.63		LRC40_HUMAN (165-308): 1.25e-11: 70.9: 25.83
+	At
		1114702 TDR_ARATH (34-312): 8.79e-21: 97.2: 14.24		ERECT_ARATH (255-502): 5.38e-11: 69: 12.80
+	At
		186962 BRI1_ARATH (11-320): 3.49e-18: 89.1: 13.03		ERL2_ARATH (255-494): 9.48e-10: 65.2: 13.64