Interactor 1: SOCS2 (O14508)
Suppressor of cytokine signaling 2 (SOCS-2) (Cytokine-inducible SH2 protein 2) (CIS-2) (STAT-induced STAT inhibitor 2) (SSI-2)
Gene: SOCS2
Interactor 2: TYK2 (P29597)
Non-receptor tyrosine-protein kinase TYK2 (EC 2.7.10.2)
Gene: TYK2
Species: Homo sapiens
Source: biogrid
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.38 | 1.00 | 0.618 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 28496097 |
| Identification Methods | affinity chromatography technology |
| Interaction Type | physical association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | FERM_F1~SH2, PK_Tyr_Ser-Thr~SH2 |
| Common GO terms | GO:0005131 - growth hormone receptor binding GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0007259 - cell surface receptor signaling pathway via JAK-STAT GO:0035556 - intracellular signal transduction |
| Homologous interactions | 20 |
Homologous interactions (Top 20)
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Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
