HitPredict

Interactor 1: SOCS7 (O14512)
Suppressor of cytokine signaling 7 (SOCS-7) (Nck, Ash and phospholipase C gamma-binding protein) (Nck-associated protein 4) (NAP-4)
Gene: SOCS7

Interactor 2: ABI1 (Q8IZP0)
Abl interactor 1 (Abelson interactor 1) (Abi-1) (Abl-binding protein 4) (AblBP4) (Eps8 SH3 domain-binding protein) (Eps8-binding protein) (Nap1-binding protein) (Nap1BP) (Spectrin SH3 domain-binding protein 1) (e3B1)
Gene: ABI1

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	1.00	0.647

Property	Details
Experiments	20598684
Identification Methods	array technology
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	SH2~SH3_1
Common GO terms	GO:0005634 - nucleus GO:0005829 - cytosol GO:0017124 - SH3 domain binding
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 581 Hs			1 508
+	Hs
		146664 SOCS7_HUMAN (1-581): 0: 569: 100.00		VINEX_HUMAN (229-504): 5.02e-15: 79.8: 15.58
+	Mm
		1257618 SOCS7_MOUSE (1-581): 0: 546: 96.39		VINEX_MOUSE (220-504): 3.43e-17: 86.7: 13.40
+	Hs
		146683 SOCS7_HUMAN (1-581): 0: 569: 100.00		SH3R1_HUMAN (244-503): 3.15e-09: 61.6: 17.28
+	Hs
		802656 CRK_HUMAN (388-568): 5.06e-51: 179: 20.77		ABI1_HUMAN (1-508): 3.82e-124: 374: 100.00
+	Hs
		802871 CRKL_HUMAN (392-566): 1.61e-37: 142: 18.75		ABI1_HUMAN (1-508): 3.82e-124: 374: 100.00
+	Hs
		655418 P85A_HUMAN (371-499): 2.26e-14: 78.5: 17.42		ABI1_HUMAN (1-508): 3.82e-124: 374: 100.00
+	Hs
		1224626 P55G_HUMAN (389-523): 3.91e-14: 76.9: 21.32		ABI1_HUMAN (1-508): 3.82e-124: 374: 100.00
+	Hs
		129316 P85B_HUMAN (389-493): 9.45e-14: 76.2: 23.59		ABI1_HUMAN (1-508): 3.82e-124: 374: 100.00
+	Mm
		643107 P85A_MOUSE (371-499): 2.26e-14: 78.5: 17.42		ABI1_MOUSE (1-508): 1.42e-122: 369: 91.93
+	Hs
		802771 CRK_HUMAN (388-568): 5.06e-51: 179: 20.77		ASAP1_HUMAN (107-505): 8.23e-33: 135: 16.83
+	Hs
		802603 CRK_HUMAN (388-568): 5.06e-51: 179: 20.77		LASP1_HUMAN (285-503): 9.91e-33: 127: 19.28
+	Hs
		802918 CRKL_HUMAN (392-566): 1.61e-37: 142: 18.75		ASAP1_HUMAN (107-505): 8.23e-33: 135: 16.83
+	Hs
		802801 CRK_HUMAN (388-568): 5.06e-51: 179: 20.77		CD2AP_HUMAN (451-508): 2.26e-14: 77.9: 40.68
+	Hs
		655502 P85A_HUMAN (371-499): 2.26e-14: 78.5: 17.42		ASAP1_HUMAN (107-505): 8.23e-33: 135: 16.83
+	Hs
		166032 P85A_HUMAN (371-499): 2.26e-14: 78.5: 17.42		SYNJ2_HUMAN (39-458): 2.1e-26: 115: 13.88
+	Hs
		655386 P85A_HUMAN (371-499): 2.26e-14: 78.5: 17.42		ITSN1_HUMAN (399-504): 1.82e-09: 62.5: 20.35