HitPredict

Interactor 1: AGRB1 (O14514)
Adhesion G protein-coupled receptor B1 (Brain-specific angiogenesis inhibitor 1) [Cleaved into: Vasculostatin-40 (Vstat40); Vasculostatin-120 (Vstat120)]
Gene: ADGRB1

Interactor 2: DLG4 (P78352)
Disks large homolog 4 (Postsynaptic density protein 95) (PSD-95) (Synapse-associated protein 90) (SAP-90) (SAP90)
Gene: DLG4

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.52	0.60	0.563

Property	Details
Experiments	11937501, 23782696
Identification Methods	affinity chromatography technology, unspecified method
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane GO:0007165 - signal transduction GO:0014069 - postsynaptic density GO:0030165 - PDZ domain binding GO:0043197 - dendritic spine
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 1584 Hs			1 724
+	Mm
		1112552 AGRB1_MOUSE (1-1584): 0: 1162: 94.07		DLG4_MOUSE (1-724): 0: 667: 99.59
+	Mm
		1143383 AGRB3_MOUSE (43-1584): 0: 900: 46.81		DLG4_MOUSE (1-724): 0: 667: 99.59
+	Hs
		225263 AGRB2_HUMAN (16-1584): 0: 763: 39.28		DLG4_HUMAN (1-724): 0: 667: 100.00
+	Mm
		1143430 AGRB2_MOUSE (16-1584): 0: 744: 39.40		DLG4_MOUSE (1-724): 0: 667: 99.59
+	Hs
		146753 AGRB1_HUMAN (1-1584): 0: 1140: 100.00		DLG1_HUMAN (147-465): 1.89e-19: 95.5: 17.93
+	Mm
		1143371 AGRL1_MOUSE (581-1472): 1.07e-161: 531: 20.16		DLG4_MOUSE (1-724): 0: 667: 99.59
+	Mm
		1143372 AGRL3_MOUSE (561-1472): 4.43e-159: 525: 18.69		DLG4_MOUSE (1-724): 0: 667: 99.59
+	Mm
		722927 CRFR1_MOUSE (890-1207): 1.15e-84: 285: 22.05		DLG4_MOUSE (1-724): 0: 667: 99.59
+	Mm
		722926 CRFR1_MOUSE (890-1207): 1.15e-84: 285: 22.05		DLG3_MOUSE (20-724): 0: 583: 64.08
+	Hs
		1021530 AGRA3_HUMAN (556-1412): 3.59e-89: 321: 16.43		DLG1_HUMAN (147-465): 1.89e-19: 95.5: 17.93