HitPredict

Interactor 1: CDKA1 (O14519)
Cyclin-dependent kinase 2-associated protein 1 (CDK2-associated protein 1) (Deleted in oral cancer 1) (DOC-1) (Putative oral cancer suppressor)
Gene: CDK2AP1

Interactor 2: CHD3 (Q12873)
Chromodomain-helicase-DNA-binding protein 3 (CHD-3) (EC 3.6.4.12) (ATP-dependent helicase CHD3) (Mi-2 autoantigen 240 kDa protein) (Mi2-alpha) (Zinc finger helicase) (hZFH)
Gene: CHD3

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.85	0.60	0.716

Property	Details
Experiments	28977666, 26496610, 24981860, 33961781, 25123934
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation, pull down
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000785 - chromatin GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005737 - cytoplasm GO:0016581 - NuRD complex
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 115 Hs			1 2000
+	Hs
		279797 CDKA2_HUMAN (19-115): 6.1e-40: 131: 66.00		CHD3_HUMAN (1-2000): 0: 1917: 100.00
+	Hs
		146841 CDKA1_HUMAN (1-115): 1.29e-60: 183: 100.00		CHD5_HUMAN (43-1961): 0: 1610: 66.45
+	Hs
		279811 CDKA2_HUMAN (19-115): 6.1e-40: 131: 66.00		CHD5_HUMAN (43-1961): 0: 1610: 66.45
+	Hs
		146817 CDKA1_HUMAN (1-115): 1.29e-60: 183: 100.00		CHD4_HUMAN (132-1922): 0: 1552: 69.84
+	Hs
		279803 CDKA2_HUMAN (19-115): 6.1e-40: 131: 66.00		CHD4_HUMAN (132-1922): 0: 1552: 69.84
+	Dm
		332908 Q9VZ27_DROME (37-114): 3.5e-27: 102: 58.97		CHDM_DROME (78-1944): 0: 1408: 52.01
+	Dm
		115148 M9PEA2_DROME (37-114): 1.29e-26: 101: 58.97		CHDM_DROME (78-1944): 0: 1408: 52.01
+	Hs
		146775 CDKA1_HUMAN (1-115): 1.29e-60: 183: 100.00		SMCA5_HUMAN (584-1612): 0: 778: 27.17
+	Hs
		146802 CDKA1_HUMAN (1-115): 1.29e-60: 183: 100.00		SMCA1_HUMAN (622-1597): 0: 776: 28.08