HitPredict

Interactor 1: CDKA1 (O14519)
Cyclin-dependent kinase 2-associated protein 1 (CDK2-associated protein 1) (Deleted in oral cancer 1) (DOC-1) (Putative oral cancer suppressor)
Gene: CDK2AP1

Interactor 2: HDAC2 (Q92769)
Histone deacetylase 2 (HD2) (EC 3.5.1.98) (Protein deacylase HDAC2) (EC 3.5.1.-)
Gene: HDAC2

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.92	0.60	0.745

Property	Details
Experiments	26496610, 24981860, 33961781, 20523938, 21258344, 23752268, 25123934
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation, pull down
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000785 - chromatin GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005737 - cytoplasm GO:0016581 - NuRD complex
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 115 Hs			1 488
+	Hs
		279813 CDKA2_HUMAN (19-115): 6.1e-40: 131: 66.00		HDAC2_HUMAN (1-488): 0: 707: 100.00
+	Hs
		146816 CDKA1_HUMAN (1-115): 1.29e-60: 183: 100.00		HDAC1_HUMAN (1-443): 0: 642: 90.07
+	Hs
		279800 CDKA2_HUMAN (19-115): 6.1e-40: 131: 66.00		HDAC1_HUMAN (1-443): 0: 642: 90.07
+	Hs
		146773 CDKA1_HUMAN (1-115): 1.29e-60: 183: 100.00		HDAC3_HUMAN (10-431): 0: 574: 58.26
+	Dm
		1276557 Q9VZ27_DROME (37-114): 3.5e-27: 102: 58.97		HDAC1_DROME (5-472): 0: 653: 77.92
+	Dm
		115159 M9PEA2_DROME (37-114): 1.29e-26: 101: 58.97		HDAC1_DROME (5-472): 0: 653: 77.92