HitPredict

Interactor 1: FCHO1 (O14526)
F-BAR domain only protein 1
Gene: FCHO1

Interactor 2: ITSN1 (Q15811)
Intersectin-1 (SH3 domain-containing protein 1A) (SH3P17)
Gene: ITSN1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	1.00	0.647

Property	Details
Experiments	27237791
Identification Methods	pull down
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	FCH~SH3_9
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0005886 - plasma membrane GO:0005905 - clathrin-coated pit
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 889 Hs			1 1721
+	Hs
		1001577 FCHO2_HUMAN (1-889): 8.07e-177: 533: 43.23		ITSN1_HUMAN (1-1721): 0: 897: 100.00
+	Hs
		1078901 SGIP1_HUMAN (211-888): 1.22e-83: 288: 27.31		ITSN1_HUMAN (1-1721): 0: 897: 100.00
+	Hs
		1078897 FNBP1_HUMAN (8-453): 8.22e-59: 214: 13.35		ITSN1_HUMAN (1-1721): 0: 897: 100.00
+	Hs
		1078931 PACN3_HUMAN (4-335): 1.02e-58: 208: 17.88		ITSN1_HUMAN (1-1721): 0: 897: 100.00
+	Hs
		297971 FCSD2_HUMAN (14-607): 6.45e-50: 190: 10.78		ITSN1_HUMAN (1-1721): 0: 897: 100.00
+	Hs
		1309721 SGIP1_HUMAN (211-888): 1.22e-83: 288: 27.31		ITSN2_HUMAN (1-1720): 0: 723: 54.73
+	Hs
		298006 FCSD2_HUMAN (14-607): 6.45e-50: 190: 10.78		ITSN2_HUMAN (1-1720): 0: 723: 54.73
+	Hs
		147194 FCHO1_HUMAN (1-889): 0: 549: 100.00		EP15R_HUMAN (545-929): 2.95e-11: 70.8: 14.14
+	Hs
		147146 FCHO1_HUMAN (1-889): 0: 549: 100.00		EPS15_HUMAN (529-913): 1.04e-10: 68.9: 12.69
+	Hs
		147143 FCHO1_HUMAN (1-889): 0: 549: 100.00		NCK1_HUMAN (895-1055): 6.44e-09: 62: 27.75
+	Hs
		1001598 FCHO2_HUMAN (1-889): 8.07e-177: 533: 43.23		EP15R_HUMAN (545-929): 2.95e-11: 70.8: 14.14
+	Hs
		787902 FCHO2_HUMAN (1-889): 8.07e-177: 533: 43.23		EPS15_HUMAN (529-913): 1.04e-10: 68.9: 12.69
+	Mm
		788006 SGIP1_MOUSE (211-888): 4.38e-81: 280: 27.31		EPS15_MOUSE (14-484): 1.37e-37: 156: 16.77
+	Hs
		1309722 SGIP1_HUMAN (211-888): 1.22e-83: 288: 27.31		EP15R_HUMAN (545-929): 2.95e-11: 70.8: 14.14
+	Hs
		787963 SGIP1_HUMAN (211-888): 1.22e-83: 288: 27.31		EPS15_HUMAN (529-913): 1.04e-10: 68.9: 12.69
+	Sc
		635278 SYP1_YEAST (17-874): 6.36e-51: 195: 13.84		EDE1_YEAST (105-331): 8.22e-13: 76.1: 21.52
+	Sp
		195123 SYP1_SCHPO (2-849): 2.61e-50: 192: 13.22		YHLA_SCHPO (198-300): 5.47e-13: 76.6: 35.92