HitPredict

Interactor 1: CUX2 (O14529)
Homeobox protein cut-like 2 (Homeobox protein cux-2)
Gene: CUX2

Interactor 2: WIPI3 (Q5MNZ6)
WD repeat domain phosphoinositide-interacting protein 3 (WIPI-3) (WD repeat-containing protein 45-like) (WDR45-like protein) (WD repeat-containing protein 45B) (WIPI49-like protein)
Gene: WDR45B

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.50	0.489

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1486 Hs			1 344
+	Mm
		1112826 SATB2_MOUSE (791-1284): 5.28e-55: 208: 13.59		SMU1_MOUSE (94-336): 3.5e-54: 187: 20.53
+	Hs
		620138 PAX7_HUMAN (1130-1425): 5.69e-50: 188: 17.23		WDR5_HUMAN (176-331): 4.98e-37: 137: 14.69
+	Hs
		551723 DESP_HUMAN (13-716): 2.8e-27: 123: 8.89		SMU1_HUMAN (94-336): 3.5e-54: 187: 20.53
+	Dm
		113992 M9PB30_DROME (1110-1485): 2.06e-16: 88.2: 8.51		Q9VSF0_DROME (1-328): 5.71e-60: 199: 26.52
+	Hs
		551655 DESP_HUMAN (13-716): 2.8e-27: 123: 8.89		WDR5_HUMAN (176-331): 4.98e-37: 137: 14.69
+	Hs
		551766 DESP_HUMAN (13-716): 2.8e-27: 123: 8.89		WDR5B_HUMAN (176-331): 4.21e-34: 129: 14.69
+	Mm
		903669 KMT2C_MOUSE (313-1400): 1.7e-19: 98.1: 10.43		WDR5_MOUSE (176-331): 4.98e-37: 137: 14.69
+	Hs
		1240468 MYO5C_HUMAN (150-646): 7.18e-29: 128: 8.37		POC1A_HUMAN (179-337): 2.87e-23: 101: 10.63
+	Hs
		903374 KMT2C_HUMAN (536-1430): 1.36e-13: 78.8: 9.62		WDR5_HUMAN (176-331): 4.98e-37: 137: 14.69
+	Hs
		903343 KTN1_HUMAN (3-431): 4.14e-09: 63.5: 15.34		WDR5_HUMAN (176-331): 4.98e-37: 137: 14.69
+	Hs
		551632 DESP_HUMAN (13-716): 2.8e-27: 123: 8.89		LIS1_HUMAN (1-88): 2.17e-14: 75.5: 16.85
+	Hs
		551854 DESP_HUMAN (13-716): 2.8e-27: 123: 8.89		NLE1_HUMAN (3-85): 2.81e-14: 75.5: 15.48
+	Hs
		929460 MDC1_HUMAN (324-1482): 3.77e-25: 116: 8.99		RACK1_HUMAN (126-294): 9.4e-14: 72.8: 13.87
+	Hs
		551838 DESP_HUMAN (13-716): 2.8e-27: 123: 8.89		BCAS3_HUMAN (164-259): 1.56e-09: 61.2: 25.71
+	Hs
		1056932 MDC1_HUMAN (324-1482): 3.77e-25: 116: 8.99		SNR40_HUMAN (10-82): 6.94e-09: 58.6: 14.87
+	Hs
		728492 MYH11_HUMAN (13-369): 1.74e-09: 65: 15.80		POC1A_HUMAN (179-337): 2.87e-23: 101: 10.63
+	Hs
		1271990 RAD50_HUMAN (17-453): 2.38e-15: 83.9: 14.66		FBXW7_HUMAN (213-329): 3.53e-14: 75.5: 11.19
+	Hs
		725215 MYH10_HUMAN (13-375): 2.37e-10: 67.7: 17.90		FBXW7_HUMAN (213-329): 3.53e-14: 75.5: 11.19
+	Hs
		1199845 KTN1_HUMAN (3-431): 4.14e-09: 63.5: 15.34		FBXW7_HUMAN (213-329): 3.53e-14: 75.5: 11.19
+	Hs
		929539 KTN1_HUMAN (3-431): 4.14e-09: 63.5: 15.34		RACK1_HUMAN (126-294): 9.4e-14: 72.8: 13.87