HitPredict

Interactor 1: TXND9 (O14530)
Thioredoxin domain-containing protein 9 (ATP-binding protein associated with cell differentiation) (Protein 1-4)
Gene: TXNDC9

Interactor 2: TCPE (P48643)
T-complex protein 1 subunit epsilon (TCP-1-epsilon) (CCT-epsilon) (Chaperonin containing T-complex polypeptide 1 subunit 5)
Gene: CCT5

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.60	0.628

Property	Details
Experiments	28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005813 - centrosome GO:0005829 - cytosol
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 226 Hs			1 541
+	Hs
		821406 PDCL3_HUMAN (36-224): 1.55e-40: 140: 21.88		TCPE_HUMAN (1-541): 0: 635: 100.00
+	Hs
		821193 PHLP_HUMAN (2-224): 3.51e-39: 138: 16.37		TCPE_HUMAN (1-541): 0: 635: 100.00
+	Hs
		147227 TXND9_HUMAN (1-221): 3.37e-59: 187: 100.00		TCPG_HUMAN (14-540): 0: 572: 33.15
+	Hs
		147282 TXND9_HUMAN (1-221): 3.37e-59: 187: 100.00		TCPH_HUMAN (12-539): 0: 570: 29.64
+	Hs
		147216 TXND9_HUMAN (1-221): 3.37e-59: 187: 100.00		TCPA_HUMAN (26-541): 0: 545: 32.08
+	Sc
		772927 PLP1_YEAST (21-224): 9.63e-40: 137: 29.19		TCPE_YEAST (3-540): 0: 582: 59.89
+	Dm
		1228893 VIAF1_DROME (4-212): 1.06e-39: 138: 20.76		Q9VHL2_DROME (14-541): 0: 577: 28.14
+	Hs
		826882 PDCL3_HUMAN (36-224): 1.55e-40: 140: 21.88		TCPG_HUMAN (14-540): 0: 572: 33.15
+	Hs
		1306678 PDCL3_HUMAN (36-224): 1.55e-40: 140: 21.88		TCPH_HUMAN (12-539): 0: 570: 29.64
+	Hs
		826645 PHLP_HUMAN (2-224): 3.51e-39: 138: 16.37		TCPG_HUMAN (14-540): 0: 572: 33.15
+	Hs
		1032867 PHLP_HUMAN (2-224): 3.51e-39: 138: 16.37		TCPH_HUMAN (12-539): 0: 570: 29.64
+	Hs
		573474 PDCL3_HUMAN (36-224): 1.55e-40: 140: 21.88		TCPA_HUMAN (26-541): 0: 545: 32.08
+	Sc
		792408 PLP1_YEAST (21-224): 9.63e-40: 137: 29.19		TCPH_YEAST (7-540): 0: 542: 30.30
+	Sc
		760808 PLP1_YEAST (21-224): 9.63e-40: 137: 29.19		TCPG_YEAST (12-541): 0: 540: 31.98
+	Hs
		147229 TXND9_HUMAN (1-221): 3.37e-59: 187: 100.00		TCPD_HUMAN (36-533): 1.62e-107: 333: 39.80
+	Hs
		843382 PDCL3_HUMAN (36-224): 1.55e-40: 140: 21.88		TCPD_HUMAN (36-533): 1.62e-107: 333: 39.80
+	Hs
		843184 PHLP_HUMAN (2-224): 3.51e-39: 138: 16.37		TCPD_HUMAN (36-533): 1.62e-107: 333: 39.80
+	Sc
		760947 PLP1_YEAST (21-224): 9.63e-40: 137: 29.19		TCPD_YEAST (32-533): 2.31e-99: 312: 36.89