HitPredict

Interactor 1: TXND9 (O14530)
Thioredoxin domain-containing protein 9 (ATP-binding protein associated with cell differentiation) (Protein 1-4)
Gene: TXNDC9

Interactor 2: TBA1A (Q71U36)
Tubulin alpha-1A chain (EC 3.6.5.-) (Alpha-tubulin 3) (Tubulin B-alpha-1) (Tubulin alpha-3 chain) [Cleaved into: Detyrosinated tubulin alpha-1A chain]
Gene: TUBA1A

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.88	1.00	0.941

Property	Details
Experiments	29568061, 34079125, 28514442, 33961781, 27291054, unassigned1655
Identification Methods	proximity labelling technology, affinity chromatography technology, pull down, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	Thioredoxin~Tubulin
Common GO terms	GO:0000226 - microtubule cytoskeleton organization GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 226 Hs			1 451
+	Hs
		147283 TXND9_HUMAN (1-221): 3.37e-59: 187: 100.00		TBA1C_HUMAN (1-451): 0: 726: 98.00
+	At
		667099 TRXH1_ARATH (71-163): 1.31e-31: 113: 23.71		TBA3_ARATH (1-435): 0: 793: 84.83
+	Hs
		147237 TXND9_HUMAN (1-221): 3.37e-59: 187: 100.00		TBA4A_HUMAN (1-450): 0: 717: 96.00
+	Hs
		147236 TXND9_HUMAN (1-221): 3.37e-59: 187: 100.00		TBA1B_HUMAN (1-440): 0: 715: 99.55
+	Hs
		147210 TXND9_HUMAN (1-221): 3.37e-59: 187: 100.00		TBB5_HUMAN (1-439): 0: 695: 40.77
+	Hs
		147238 TXND9_HUMAN (1-221): 3.37e-59: 187: 100.00		TBB4B_HUMAN (1-437): 0: 693: 40.50
+	Hs
		933612 PDCL3_HUMAN (36-224): 1.55e-40: 140: 21.88		TBA4A_HUMAN (1-450): 0: 717: 96.00
+	Hs
		1175173 PDCL3_HUMAN (36-224): 1.55e-40: 140: 21.88		TBA1A_HUMAN (1-440): 0: 713: 100.00
+	Mm
		933696 THIOM_MOUSE (74-173): 4.05e-34: 121: 25.49		TBA4A_MOUSE (1-450): 0: 717: 96.00