HitPredict

Interactor 1: TXND9 (O14530)
Thioredoxin domain-containing protein 9 (ATP-binding protein associated with cell differentiation) (Protein 1-4)
Gene: TXNDC9

Interactor 2: TBA1C (Q9BQE3)
Tubulin alpha-1C chain (EC 3.6.5.-) (Alpha-tubulin 6) (Tubulin alpha-6 chain) [Cleaved into: Detyrosinated tubulin alpha-1C chain]
Gene: TUBA1C

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.75	1.00	0.871

Property	Details
Experiments	28514442, 33961781, 26496610
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	Thioredoxin~Tubulin
Common GO terms	GO:0000226 - microtubule cytoskeleton organization GO:0005634 - nucleus GO:0005737 - cytoplasm
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 226 Hs			1 449
+	Hs
		147237 TXND9_HUMAN (1-221): 3.37e-59: 187: 100.00		TBA4A_HUMAN (1-448): 0: 724: 96.21
+	At
		667099 TRXH1_ARATH (71-163): 1.31e-31: 113: 23.71		TBA3_ARATH (1-435): 0: 794: 85.06
+	Hs
		147236 TXND9_HUMAN (1-221): 3.37e-59: 187: 100.00		TBA1B_HUMAN (1-439): 0: 717: 99.09
+	Hs
		147258 TXND9_HUMAN (1-221): 3.37e-59: 187: 100.00		TBA1A_HUMAN (1-439): 0: 715: 99.09
+	Hs
		147210 TXND9_HUMAN (1-221): 3.37e-59: 187: 100.00		TBB5_HUMAN (1-439): 0: 699: 41.00
+	Hs
		147238 TXND9_HUMAN (1-221): 3.37e-59: 187: 100.00		TBB4B_HUMAN (1-437): 0: 697: 40.73
+	Hs
		933612 PDCL3_HUMAN (36-224): 1.55e-40: 140: 21.88		TBA4A_HUMAN (1-448): 0: 724: 96.21
+	Hs
		1175173 PDCL3_HUMAN (36-224): 1.55e-40: 140: 21.88		TBA1A_HUMAN (1-439): 0: 715: 99.09
+	Mm
		933696 THIOM_MOUSE (74-173): 4.05e-34: 121: 25.49		TBA4A_MOUSE (1-448): 0: 724: 96.21