HitPredict

Interactor 1: TXND9 (O14530)
Thioredoxin domain-containing protein 9 (ATP-binding protein associated with cell differentiation) (Protein 1-4)
Gene: TXNDC9

Interactor 2: TBG2 (Q9NRH3)
Tubulin gamma-2 chain (Gamma-2-tubulin)
Gene: TUBG2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	1.00	0.691

Property	Details
Experiments	28514442
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	Thioredoxin~Tubulin
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005813 - centrosome GO:0005829 - cytosol
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 226 Hs			1 451
+	Hs
		147218 TXND9_HUMAN (1-221): 3.37e-59: 187: 100.00		TBG1_HUMAN (1-451): 0: 654: 97.78
+	Hs
		147236 TXND9_HUMAN (1-221): 3.37e-59: 187: 100.00		TBA1B_HUMAN (3-442): 0: 653: 31.25
+	Hs
		147210 TXND9_HUMAN (1-221): 3.37e-59: 187: 100.00		TBB5_HUMAN (3-439): 0: 652: 33.79
+	Hs
		147238 TXND9_HUMAN (1-221): 3.37e-59: 187: 100.00		TBB4B_HUMAN (3-437): 0: 651: 33.95
+	Hs
		147258 TXND9_HUMAN (1-221): 3.37e-59: 187: 100.00		TBA1A_HUMAN (3-442): 0: 651: 31.03
+	Hs
		147242 TXND9_HUMAN (1-221): 3.37e-59: 187: 100.00		TBB2A_HUMAN (3-440): 0: 648: 33.71
+	Hs
		147283 TXND9_HUMAN (1-221): 3.37e-59: 187: 100.00		TBA1C_HUMAN (3-451): 0: 648: 30.85
+	Hs
		614133 PDCL3_HUMAN (36-224): 1.55e-40: 140: 21.88		TBG1_HUMAN (1-451): 0: 654: 97.78
+	Hs
		1175173 PDCL3_HUMAN (36-224): 1.55e-40: 140: 21.88		TBA1A_HUMAN (3-442): 0: 651: 31.03
+	Hs
		1032880 PHLP_HUMAN (2-224): 3.51e-39: 138: 16.37		TBG2_HUMAN (1-451): 0: 651: 100.00
+	Mm
		956740 THIOM_MOUSE (74-173): 4.05e-34: 121: 25.49		TBB2A_MOUSE (3-440): 0: 648: 33.71
+	At
		1122959 PLP3A_ARATH (3-224): 1.03e-45: 153: 37.39		TBB2_ARATH (3-436): 2.09e-90: 283: 35.99
+	At
		1155164 PLP3A_ARATH (3-224): 1.03e-45: 153: 37.39		TBB3_ARATH (3-436): 2.09e-90: 283: 35.99
+	At
		623712 PLP3A_ARATH (3-224): 1.03e-45: 153: 37.39		TBB4_ARATH (3-436): 1.65e-90: 283: 35.76
+	At
		668113 PLP3A_ARATH (3-224): 1.03e-45: 153: 37.39		TBB5_ARATH (3-436): 1.76e-88: 278: 36.14
+	Sc
		361016 PLP1_YEAST (21-224): 9.63e-40: 137: 29.19		TBB_YEAST (3-442): 1.71e-87: 276: 35.60
+	At
		623710 TRXH1_ARATH (71-163): 1.31e-31: 113: 23.71		TBB4_ARATH (3-436): 1.65e-90: 283: 35.76
+	At
		667103 TRXH1_ARATH (71-163): 1.31e-31: 113: 23.71		TBB3_ARATH (3-436): 2.09e-90: 283: 35.99
+	At
		667086 TRXH1_ARATH (71-163): 1.31e-31: 113: 23.71		TBB7_ARATH (3-436): 2.26e-87: 275: 35.54