HitPredict

Interactor 1: SOCS6 (O14544)
Suppressor of cytokine signaling 6 (SOCS-6) (Cytokine-inducible SH2 protein 4) (CIS-4) (Suppressor of cytokine signaling 4) (SOCS-4)
Gene: SOCS6

Interactor 2: 1433G (P61981)
14-3-3 protein gamma (Protein kinase C inhibitor protein 1) (KCIP-1) [Cleaved into: 14-3-3 protein gamma, N-terminally processed]
Gene: YWHAG

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.44	0.60	0.515

Property	Details
Experiments	28883622
Identification Methods	proximity labelling technology, affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 535 Hs			1 247
+	Hs
		147513 SOCS6_HUMAN (1-535): 0: 701: 100.00		1433F_HUMAN (1-246): 2.5e-135: 382: 86.99
+	Hs
		147487 SOCS6_HUMAN (1-535): 0: 701: 100.00		1433T_HUMAN (2-245): 5.53e-105: 305: 70.33
+	Hs
		411661 LCK_HUMAN (258-495): 3.81e-54: 192: 17.20		1433E_HUMAN (1-244): 2.02e-141: 398: 63.53
+	Hs
		904702 TENS3_HUMAN (161-475): 7.47e-45: 171: 18.08		1433G_HUMAN (1-247): 3.15e-139: 392: 100.00
+	Hs
		982129 TENS3_HUMAN (161-475): 7.47e-45: 171: 18.08		1433F_HUMAN (1-246): 2.5e-135: 382: 86.99
+	Hs
		411666 LCK_HUMAN (258-495): 3.81e-54: 192: 17.20		1433Z_HUMAN (2-245): 2.39e-108: 314: 74.59
+	Hs
		411605 LCK_HUMAN (258-495): 3.81e-54: 192: 17.20		1433T_HUMAN (2-245): 5.53e-105: 305: 70.33
+	Hs
		683433 TENS3_HUMAN (161-475): 7.47e-45: 171: 18.08		1433B_HUMAN (2-247): 1.91e-109: 317: 75.40
+	Hs
		411616 LCK_HUMAN (258-495): 3.81e-54: 192: 17.20		1433S_HUMAN (2-245): 1.86e-98: 289: 65.16
+	Hs
		129265 P85B_HUMAN (380-491): 1.89e-14: 78.2: 27.68		1433E_HUMAN (1-244): 2.02e-141: 398: 63.53
+	Mm
		140059 P85B_MOUSE (380-491): 1.95e-14: 78.2: 27.68		1433E_MOUSE (1-244): 2.02e-141: 398: 63.53
+	Hs
		646992 TENS3_HUMAN (161-475): 7.47e-45: 171: 18.08		1433T_HUMAN (2-245): 5.53e-105: 305: 70.33
+	Hs
		655301 P85A_HUMAN (384-496): 1.31e-12: 72.4: 23.89		1433E_HUMAN (1-244): 2.02e-141: 398: 63.53
+	Hs
		655299 P85A_HUMAN (384-496): 1.31e-12: 72.4: 23.89		1433G_HUMAN (1-247): 3.15e-139: 392: 100.00
+	Hs
		684109 TENS3_HUMAN (161-475): 7.47e-45: 171: 18.08		1433S_HUMAN (2-245): 1.86e-98: 289: 65.16
+	Hs
		147394 SOCS3_HUMAN (372-533): 7.64e-38: 140: 26.56		1433T_HUMAN (2-245): 5.53e-105: 305: 70.33
+	Hs
		129216 P85B_HUMAN (380-491): 1.89e-14: 78.2: 27.68		1433B_HUMAN (2-247): 1.91e-109: 317: 75.40
+	Hs
		129271 P85B_HUMAN (380-491): 1.89e-14: 78.2: 27.68		1433Z_HUMAN (2-245): 2.39e-108: 314: 74.59
+	Hs
		655308 P85A_HUMAN (384-496): 1.31e-12: 72.4: 23.89		1433Z_HUMAN (2-245): 2.39e-108: 314: 74.59
+	Hs
		129204 P85B_HUMAN (380-491): 1.89e-14: 78.2: 27.68		1433T_HUMAN (2-245): 5.53e-105: 305: 70.33