HitPredict

Interactor 1: HSPB6 (O14558)
Heat shock protein beta-6 (HspB6) (Heat shock 20 kDa-like protein p20) (Heat shock protein family B member 6)
Gene: HSPB6

Interactor 2: HSPB1 (P04792)
Heat shock protein beta-1 (HspB1) (28 kDa heat shock protein) (Estrogen-regulated 24 kDa protein) (Heat shock 27 kDa protein) (HSP 27) (Heat shock protein family B member 1) (Stress-responsive protein 27) (SRP27)
Gene: HSPB1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.74 1.00 0.861

The method score is based on:

Property Details
Experiments 26186194, 28514442, 33961781
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains Crystallin~HSP20, HSP20~HSP20
Common GO terms GO:0005634 - nucleus
GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0009408 - response to heat
GO:0042026 - protein refolding
and 6 others

more...
Homologous interactions 15

Homologous interactions

Color coding for hit scores

1 160
Hs

1 205
+ Hs
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+ Rn
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+ Hs
+ Bt
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+ Hs
+ Hs
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+ Rn

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Last updated: 15 Jul 2024