HitPredict

Interactor 1: CTRO (O14578)
Citron Rho-interacting kinase (CRIK) (EC 2.7.11.1) (Serine/threonine-protein kinase 21)
Gene: CIT

Interactor 2: BRE1B (O75150)
E3 ubiquitin-protein ligase BRE1B (BRE1-B) (EC 2.3.2.27) (95 kDa retinoblastoma-associated protein) (RBP95) (RING finger protein 40) (RING-type E3 ubiquitin transferase BRE1B)
Gene: RNF40

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	31586073
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0016020 - membrane GO:0046872 - metal ion binding
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 2027 Hs			1 1001
+	Hs
		148460 CTRO_HUMAN (1-2027): 0: 1212: 100.00		MYH9_HUMAN (271-982): 5.38e-32: 137: 10.53
+	Hs
		148461 CTRO_HUMAN (1-2027): 0: 1212: 100.00		MYH10_HUMAN (1-443): 3.14e-19: 96.3: 12.58
+	Hs
		148466 CTRO_HUMAN (1-2027): 0: 1212: 100.00		MYH11_HUMAN (563-983): 2.12e-18: 93.6: 10.66
+	Hs
		148126 CTRO_HUMAN (1-2027): 0: 1212: 100.00		CTRO_HUMAN (248-944): 2.51e-10: 67.2: 14.91
+	Hs
		148359 CTRO_HUMAN (1-2027): 0: 1212: 100.00		DESP_HUMAN (233-945): 1.26e-09: 64.9: 14.36
+	Hs
		116964 SGK1_HUMAN (59-407): 8.42e-121: 390: 31.37		MYH1_HUMAN (465-982): 1.43e-19: 97.1: 9.41
+	Hs
		725079 ST38L_HUMAN (74-430): 6.61e-69: 242: 35.79		MYH9_HUMAN (271-982): 5.38e-32: 137: 10.53
+	Hs
		149340 LATS2_HUMAN (103-400): 4.87e-58: 222: 39.26		CTRO_HUMAN (248-944): 2.51e-10: 67.2: 14.91
+	Hs
		724810 ROCK1_HUMAN (1051-1566): 8.4e-21: 102: 10.08		MYH9_HUMAN (271-982): 5.38e-32: 137: 10.53
+	Rn
		92843 ROCK2_RAT (864-1552): 1.94e-37: 156: 12.16		CTRO_RAT (318-932): 1.01e-12: 74.9: 15.80