HitPredict

Interactor 1: CTRO (O14578)
Citron Rho-interacting kinase (CRIK) (EC 2.7.11.1) (Serine/threonine-protein kinase 21)
Gene: CIT

Interactor 2: MYL9 (P24844)
Myosin regulatory light polypeptide 9 (20 kDa myosin light chain) (LC20) (MLC-2C) (Myosin RLC) (Myosin regulatory light chain 2, smooth muscle isoform) (Myosin regulatory light chain 9) (Myosin regulatory light chain MRLC1)
Gene: MYL9

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	31586073
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	EF-hand_7~Pkinase
Common GO terms	GO:0005829 - cytosol
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 2027 Hs			1 172
+	Hs
		148135 CTRO_HUMAN (1-2027): 0: 1212: 100.00		ML12B_HUMAN (1-172): 6.88e-67: 203: 93.02
+	Hs
		148383 CTRO_HUMAN (1-2027): 0: 1212: 100.00		ML12A_HUMAN (15-172): 5.65e-65: 198: 94.30
+	Hs
		624380 AKT3_HUMAN (44-417): 2.46e-124: 403: 30.31		MYL9_HUMAN (1-172): 1.16e-66: 202: 100.00
+	At
		187626 CIPKD_ARATH (74-544): 3.7e-117: 383: 22.43		CDPKF_ARATH (1-166): 1.63e-53: 179: 23.53
+	Dm
		116375 M9PI41_DROME (554-1859): 9.84e-96: 347: 15.45		SQH_DROME (1-172): 4.82e-61: 188: 80.46
+	At
		1104924 CDPK4_ARATH (73-547): 7.34e-127: 410: 20.63		CDPK4_ARATH (37-172): 9.44e-14: 69.9: 17.69
+	At
		1105900 CDPKB_ARATH (75-547): 1.64e-126: 409: 20.71		CDPKB_ARATH (37-172): 5.61e-13: 67.5: 17.01
+	Gm
		1196117 Q84P28_SOYBN (80-547): 1.63e-126: 409: 20.93		Q84P28_SOYBN (18-111): 1.95e-10: 60.2: 18.18
+	At
		989461 KIN10_ARATH (96-367): 2.92e-120: 392: 27.84		CDPK1_ARATH (62-172): 5.02e-14: 70.6: 20.18
+	At
		483143 CIPKO_ARATH (87-529): 6.92e-118: 383: 20.89		CALM4_ARATH (102-171): 6.63e-16: 72.2: 27.14
+	At
		886601 CIPKO_ARATH (87-529): 6.92e-118: 383: 20.89		CALM7_ARATH (20-93): 1.06e-09: 56: 24.36
+	At
		976670 CIPKO_ARATH (87-529): 6.92e-118: 383: 20.89		CALM6_ARATH (20-93): 1.97e-09: 55.2: 23.08
+	Hs
		580656 MRCKA_HUMAN (536-1061): 4.38e-32: 139: 11.82		ML12A_HUMAN (15-172): 5.65e-65: 198: 94.30
+	Hs
		254439 ROCK2_HUMAN (864-1552): 1.55e-37: 157: 12.16		MLRV_HUMAN (9-166): 3.21e-54: 171: 57.23
+	At
		483153 Q9LW66_ARATH (88-455): 9.25e-65: 233: 35.18		CALM4_ARATH (102-171): 6.63e-16: 72.2: 27.14
+	At
		886616 Q9LW66_ARATH (88-455): 9.25e-65: 233: 35.18		CALM7_ARATH (20-93): 1.06e-09: 56: 24.36
+	At
		976679 Q9LW66_ARATH (88-455): 9.25e-65: 233: 35.18		CALM6_ARATH (20-93): 1.97e-09: 55.2: 23.08
+	Dm
		576952 Q961D4_DROME (682-1366): 1.1e-37: 158: 11.24		MLR_DROME (3-163): 7.57e-30: 110: 40.61