HitPredict

Interactor 1: CTRO (O14578)
Citron Rho-interacting kinase (CRIK) (EC 2.7.11.1) (Serine/threonine-protein kinase 21)
Gene: CIT

Interactor 2: MED1 (Q15648)
Mediator of RNA polymerase II transcription subunit 1 (Activator-recruited cofactor 205 kDa component) (ARC205) (Mediator complex subunit 1) (Peroxisome proliferator-activated receptor-binding protein) (PBP) (PPAR-binding protein) (Thyroid hormone receptor-associated protein complex 220 kDa component) (Trap220) (Thyroid receptor-interacting protein 2) (TR-interacting protein 2) (TRIP-2) (Vitamin D receptor-interacting protein complex component DRIP205) (p53 regulatory protein RB18A)
Gene: MED1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	31586073
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0001223 - transcription coactivator binding GO:0016020 - membrane
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 2027 Hs			1 1581
+	Hs
		149481 CTRO_HUMAN (1-2027): 0: 1212: 100.00		PCLO_HUMAN (965-1551): 5.81e-17: 89.8: 11.57
+	Hs
		148818 CTRO_HUMAN (1-2027): 0: 1212: 100.00		MDC1_HUMAN (751-1577): 1.19e-16: 88.6: 8.40
+	Hs
		148941 CTRO_HUMAN (1-2027): 0: 1212: 100.00		NIPBL_HUMAN (984-1563): 7.42e-16: 86.1: 16.01
+	Dm
		1370292 Q9VTY8_DROME (554-1859): 1.42e-95: 346: 15.45		Q9VLS7_DROME (558-1479): 2.66e-10: 67.8: 9.81
+	Hs
		1154090 ST38L_HUMAN (74-430): 6.61e-69: 242: 35.79		NIPBL_HUMAN (984-1563): 7.42e-16: 86.1: 16.01
+	Hs
		1069616 STK38_HUMAN (87-430): 1.1e-68: 241: 36.29		NIPBL_HUMAN (984-1563): 7.42e-16: 86.1: 16.01
+	Hs
		164701 ST38L_HUMAN (74-430): 6.61e-69: 242: 35.79		MAST4_HUMAN (1031-1535): 2.51e-10: 67.7: 13.92
+	Dm
		1370328 Q9VXE3_DROME (682-1366): 5.51e-38: 158: 11.24		Q9VLS7_DROME (558-1479): 2.66e-10: 67.8: 9.81