HitPredict

Interactor 1: TIM9 (Q9VYD7)
Mitochondrial import inner membrane translocase subunit Tim9
Gene: Tim9a

Interactor 2: TIM10 (Q9W2D6)
Mitochondrial import inner membrane translocase subunit Tim10
Gene: TIM10

Species: Drosophila melanogaster

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.54	1.00	0.737

Property	Details
Experiments	22036573, 38944040
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	zf-Tim10_DDP~zf-Tim10_DDP
Common GO terms	GO:0042719 - mitochondrial intermembrane space chaperone complex GO:0042721 - TIM22 mitochondrial import inner membrane insertion complex GO:0045039 - protein insertion into mitochondrial inner membrane GO:0046872 - metal ion binding
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 95 Dm			1 92
+	Mm
		967290 TIM9_MOUSE (14-95): 1.43e-30: 105: 56.10		TIM10_MOUSE (15-90): 3.25e-31: 106: 71.05
+	Hs
		967288 TIM9_HUMAN (14-95): 3.87e-30: 104: 56.10		TIM10_HUMAN (15-90): 3.25e-31: 106: 71.05
+	Sc
		267940 TIM9_YEAST (19-78): 2.09e-20: 79.4: 48.33		TIM12_YEAST (9-91): 9.3e-35: 116: 32.14
+	Hs
		967287 T10B_HUMAN (18-77): 8.81e-24: 88.3: 28.33		TIM10_HUMAN (15-90): 3.25e-31: 106: 71.05
+	Sc
		267948 TIM9_YEAST (19-78): 2.09e-20: 79.4: 48.33		TIM10_YEAST (5-81): 3.4e-28: 99.1: 40.26