HitPredict

Interactor 1: CTRO (O14578)
Citron Rho-interacting kinase (CRIK) (EC 2.7.11.1) (Serine/threonine-protein kinase 21)
Gene: CIT

Interactor 2: RB6I2 (Q8IUD2)
ELKS/Rab6-interacting/CAST family member 1 (ERC-1) (Rab6-interacting protein 2)
Gene: ERC1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	31586073
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0030165 - PDZ domain binding
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 2027 Hs			1 1116
+	Hs
		148466 CTRO_HUMAN (1-2027): 0: 1212: 100.00		MYH11_HUMAN (2-719): 7.51e-34: 144: 10.30
+	Hs
		148460 CTRO_HUMAN (1-2027): 0: 1212: 100.00		MYH9_HUMAN (2-736): 1.6e-33: 142: 9.92
+	Hs
		148126 CTRO_HUMAN (1-2027): 0: 1212: 100.00		CTRO_HUMAN (156-792): 2.47e-18: 93.5: 12.63
+	Hs
		148461 CTRO_HUMAN (1-2027): 0: 1212: 100.00		MYH10_HUMAN (664-1113): 2.61e-18: 93.3: 12.09
+	Hs
		148359 CTRO_HUMAN (1-2027): 0: 1212: 100.00		DESP_HUMAN (457-1104): 2.2e-09: 64.3: 13.22
+	Hs
		149126 CTRO_HUMAN (1-2027): 0: 1212: 100.00		MY18A_HUMAN (439-976): 3.58e-09: 63.5: 18.73
+	Rn
		92843 CTRO_RAT (1-2027): 0: 1136: 93.58		ROCK2_RAT (162-847): 7.58e-09: 62.4: 19.87
+	Hs
		682193 AKT2_HUMAN (44-403): 6.67e-122: 396: 31.47		RB6I2_HUMAN (1-1116): 2.23e-82: 293: 100.00
+	Hs
		116964 SGK1_HUMAN (59-407): 8.42e-121: 390: 31.37		MYH1_HUMAN (390-1116): 2.17e-34: 146: 13.62
+	Hs
		1216162 LATS2_HUMAN (103-400): 4.87e-58: 222: 39.26		RB6I2_HUMAN (1-1116): 2.23e-82: 293: 100.00
+	Ce
		218454 WARTS_CAEEL (8-429): 1.75e-135: 449: 29.92		O44490_CAEEL (161-834): 3.6e-09: 63.2: 20.15
+	Hs
		725079 ST38L_HUMAN (74-430): 6.61e-69: 242: 35.79		MYH9_HUMAN (2-736): 1.6e-33: 142: 9.92
+	Hs
		149340 LATS2_HUMAN (103-400): 4.87e-58: 222: 39.26		CTRO_HUMAN (156-792): 2.47e-18: 93.5: 12.63
+	Bt
		1100183 ROCK2_BOVIN (849-1552): 9.07e-35: 148: 8.35		ROCK2_BOVIN (193-847): 1.07e-09: 65.1: 20.39
+	Rn
		222476 MRCKA_RAT (536-1070): 1.62e-33: 144: 11.97		MRCKB_RAT (362-928): 3.7e-10: 66.6: 22.66
+	Rn
		1186812 MRCKB_RAT (566-1070): 2.51e-33: 143: 12.74		MRCKB_RAT (362-928): 3.7e-10: 66.6: 22.66
+	Hs
		1137898 MRCKA_HUMAN (536-1061): 4.38e-32: 139: 11.82		KI20B_HUMAN (386-907): 1.4e-10: 68.2: 21.17
+	Hs
		1268126 MRCKB_HUMAN (569-1070): 4.13e-33: 143: 12.04		MY18A_HUMAN (439-976): 3.58e-09: 63.5: 18.73
+	Ce
		136548 MRCK_CAEEL (598-1048): 6.86e-28: 125: 9.74		O44490_CAEEL (161-834): 3.6e-09: 63.2: 20.15