HitPredict

Interactor 1: PCDBC (Q9Y5F1)
Protocadherin beta-12 (PCDH-beta-12)
Gene: PCDHB12

Interactor 2: PCDBB (Q9Y5F2)
Protocadherin beta-11 (PCDH-beta-11)
Gene: PCDHB11

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.73	1.00	0.855

Property	Details
Experiments	28514442, 33961781, unassigned3799
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	Cadherin~Cadherin, Cadherin~Cadherin_2
Common GO terms	GO:0005509 - calcium ion binding GO:0005886 - plasma membrane GO:0007155 - cell adhesion GO:0007156 - homophilic cell adhesion via plasma membrane adhesion molecules GO:0007399 - nervous system development
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 795 Hs			1 797
+	Hs
		1491532 PCDBB_HUMAN (1-795): 0: 972: 88.81		PCDB5_HUMAN (1-796): 0: 1019: 73.74
+	Hs
		1491531 PCDB5_HUMAN (1-795): 0: 970: 74.21		PCDB3_HUMAN (1-796): 0: 1013: 75.25
+	Hs
		1491569 PCDBB_HUMAN (1-795): 0: 972: 88.81		PCDBD_HUMAN (1-797): 0: 1009: 73.94
+	Hs
		1462144 PCDBB_HUMAN (1-795): 0: 972: 88.81		PCDB8_HUMAN (1-797): 0: 1007: 74.44
+	Hs
		1491523 PCDBC_HUMAN (1-795): 0: 979: 100.00		PCDB7_HUMAN (1-795): 0: 984: 72.96
+	Hs
		1462152 PCDBB_HUMAN (1-795): 0: 972: 88.81		PCDBA_HUMAN (1-797): 0: 979: 72.47
+	Hs
		1491576 PCDBC_HUMAN (1-795): 0: 979: 100.00		PCDGH_HUMAN (26-796): 0: 923: 43.50
+	Hs
		1491578 PCDBC_HUMAN (1-795): 0: 979: 100.00		PCDG5_HUMAN (1-792): 0: 922: 43.84
+	Hs
		1491581 PCDBB_HUMAN (1-795): 0: 972: 88.81		PCDGH_HUMAN (26-796): 0: 923: 43.50
+	Hs
		1491583 PCDBB_HUMAN (1-795): 0: 972: 88.81		PCDG5_HUMAN (1-792): 0: 922: 43.84
+	Hs
		1491534 PCDB5_HUMAN (1-795): 0: 970: 74.21		PCDGH_HUMAN (26-796): 0: 923: 43.50
+	Hs
		1491537 PCDB5_HUMAN (1-795): 0: 970: 74.21		PCDG6_HUMAN (1-792): 0: 920: 42.13
+	Hs
		1491577 PCDBC_HUMAN (1-795): 0: 979: 100.00		PCDGD_HUMAN (1-792): 0: 903: 40.54
+	Hs
		1491582 PCDBB_HUMAN (1-795): 0: 972: 88.81		PCDGD_HUMAN (1-792): 0: 903: 40.54
+	Hs
		1491536 PCDB5_HUMAN (1-795): 0: 970: 74.21		PCDGD_HUMAN (1-792): 0: 903: 40.54
+	Hs
		1491584 PCDBB_HUMAN (1-795): 0: 972: 88.81		PCDA8_HUMAN (1-792): 0: 890: 38.48
+	Hs
		1491585 PCDBB_HUMAN (1-795): 0: 972: 88.81		PCDA3_HUMAN (1-792): 0: 890: 38.48
+	Hs
		1491535 PCDB5_HUMAN (1-795): 0: 970: 74.21		PCDGE_HUMAN (33-767): 0: 593: 45.42
+	Hs
		1491529 PCDBC_HUMAN (1-795): 0: 979: 100.00		PCDB6_HUMAN (1-234): 7.5e-29: 125: 17.96