HitPredict

Interactor 1: CTRO (O14578)
Citron Rho-interacting kinase (CRIK) (EC 2.7.11.1) (Serine/threonine-protein kinase 21)
Gene: CIT

Interactor 2: SNX27 (Q96L92)
Sorting nexin-27
Gene: SNX27

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	1.00	0.789

Property	Details
Experiments	33961781, 34315543
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	PH~PX, PH~RA
Common GO terms	GO:0005829 - cytosol
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 2027 Hs			1 541
+	Hs
		148925 CTRO_HUMAN (1-2027): 0: 1212: 100.00		MAGI3_HUMAN (19-429): 6.34e-14: 77.3: 15.39
+	Hs
		149188 CTRO_HUMAN (1-2027): 0: 1212: 100.00		MAGI1_HUMAN (2-334): 3.18e-13: 74.9: 17.51
+	Hs
		148718 CTRO_HUMAN (1-2027): 0: 1212: 100.00		ZO1_HUMAN (4-254): 7.48e-12: 70.3: 13.97
+	Mm
		823533 CTRO_MOUSE (1-2027): 0: 1113: 93.68		SHAN3_MOUSE (44-148): 2.57e-21: 100: 36.19
+	Hs
		682200 AKT2_HUMAN (44-403): 6.67e-122: 396: 31.47		SNX27_HUMAN (1-541): 0: 625: 100.00
+	Hs
		1296964 ST38L_HUMAN (74-430): 6.61e-69: 242: 35.79		SNX27_HUMAN (1-541): 0: 625: 100.00
+	Hs
		1069638 STK38_HUMAN (87-430): 1.1e-68: 241: 36.29		SNX27_HUMAN (1-541): 0: 625: 100.00
+	Hs
		1035197 ROCK1_HUMAN (1051-1566): 8.4e-21: 102: 10.08		SNX27_HUMAN (1-541): 0: 625: 100.00
+	Rn
		193535 KS6B1_RAT (65-433): 1.61e-128: 416: 31.50		NEB1_RAT (40-375): 5.28e-41: 160: 14.43
+	Mm
		1115981 MRCKB_MOUSE (44-928): 7.57e-135: 467: 26.09		SHAN3_MOUSE (44-148): 2.57e-21: 100: 36.19
+	Ce
		88187 WARTS_CAEEL (8-429): 1.75e-135: 449: 29.92		D3YT29_CAEEL (32-299): 2.53e-11: 68.4: 15.13
+	Hs
		117007 SGK1_HUMAN (59-407): 8.42e-121: 390: 31.37		NHRF2_HUMAN (9-207): 1.8e-24: 106: 21.78
+	Hs
		1344946 LATS2_HUMAN (103-400): 4.87e-58: 222: 39.26		LIN7C_HUMAN (35-136): 1.5e-27: 111: 34.95
+	Hs
		1300675 LATS2_HUMAN (103-400): 4.87e-58: 222: 39.26		MAGI1_HUMAN (2-334): 3.18e-13: 74.9: 17.51
+	Hs
		990944 LATS2_HUMAN (103-400): 4.87e-58: 222: 39.26		ZO1_HUMAN (4-254): 7.48e-12: 70.3: 13.97
+	Mm
		936587 ROCK2_MOUSE (864-1552): 1.88e-34: 147: 10.06		NEB2_MOUSE (40-314): 1.09e-33: 138: 17.98
+	Mm
		936584 ROCK2_MOUSE (864-1552): 1.88e-34: 147: 10.06		SHAN3_MOUSE (44-148): 2.57e-21: 100: 36.19
+	Hs
		990961 MRCKB_HUMAN (569-1070): 4.13e-33: 143: 12.04		ZO1_HUMAN (4-254): 7.48e-12: 70.3: 13.97