HitPredict

Interactor 1: CTRO (O14578)
Citron Rho-interacting kinase (CRIK) (EC 2.7.11.1) (Serine/threonine-protein kinase 21)
Gene: CIT

Interactor 2: MACF1 (Q9UPN3)
Microtubule-actin cross-linking factor 1, isoforms 1/2/3/4/5 (620 kDa actin-binding protein) (ABP620) (Actin cross-linking family protein 7) (Macrophin-1) (Trabeculin-alpha)
Gene: MACF1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	31586073
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	EF-hand_7~Pkinase
Common GO terms	GO:0015629 - actin cytoskeleton GO:0016020 - membrane
Homologous interactions	15

Homologous interactions

Color coding for hit scores

	1 2027 Hs			1 7388
+	Hs
		148591 CTRO_HUMAN (1-2027): 0: 1212: 100.00		EPIPL_HUMAN (1538-2789): 1.49e-35: 154: 13.15
+	Hs
		148330 CTRO_HUMAN (1-2027): 0: 1212: 100.00		SPTB1_HUMAN (3013-4737): 1.1e-28: 131: 8.92
+	Hs
		148359 CTRO_HUMAN (1-2027): 0: 1212: 100.00		DESP_HUMAN (2737-3775): 9.21e-27: 124: 8.65
+	Hs
		148841 CTRO_HUMAN (1-2027): 0: 1212: 100.00		PLEC_HUMAN (2677-3656): 8.53e-27: 124: 8.13
+	Hs
		148722 CTRO_HUMAN (1-2027): 0: 1212: 100.00		ACTN3_HUMAN (5633-6111): 4.77e-17: 92.1: 12.20
+	Hs
		149072 CTRO_HUMAN (1-2027): 0: 1212: 100.00		SYNE1_HUMAN (343-1742): 3.05e-13: 80.2: 8.97
+	Hs
		148142 CTRO_HUMAN (1-2027): 0: 1212: 100.00		SPTN2_HUMAN (3436-4815): 1.06e-11: 74.8: 9.59
+	Hs
		148690 CTRO_HUMAN (1-2027): 0: 1212: 100.00		SPTB2_HUMAN (6378-7134): 6.05e-11: 72.5: 13.80
+	Hs
		148339 CTRO_HUMAN (1-2027): 0: 1212: 100.00		ACTN1_HUMAN (921-1398): 1.47e-10: 70.5: 9.07
+	Hs
		148786 CTRO_HUMAN (1-2027): 0: 1212: 100.00		SPTN1_HUMAN (433-1344): 7.43e-10: 68.8: 13.39
+	Hs
		149277 CTRO_HUMAN (1-2027): 0: 1212: 100.00		SPTN4_HUMAN (4289-5023): 8.23e-09: 65.5: 19.24
+	Rn
		1144340 AKT3_RAT (44-404): 7.24e-122: 395: 31.37		SPTN2_RAT (3436-4815): 6.61e-11: 72.1: 9.65
+	Hs
		809184 LATS2_HUMAN (103-400): 4.87e-58: 222: 39.26		UTRN_HUMAN (428-1437): 8.81e-11: 71.9: 13.98
+	Hs
		885258 MRCKA_HUMAN (536-1061): 4.38e-32: 139: 11.82		EPIPL_HUMAN (1538-2789): 1.49e-35: 154: 13.15
+	Hs
		623875 KPCL_HUMAN (1355-1514): 4.34e-12: 73.3: 16.36		PLEC_HUMAN (2677-3656): 8.53e-27: 124: 8.13