HitPredict

Interactor 1: COPE (O14579)
Coatomer subunit epsilon (Epsilon-coat protein) (Epsilon-COP)
Gene: COPE

Interactor 2: INSR (P06213)
Insulin receptor (IR) (EC 2.7.10.1) (CD antigen CD220) [Cleaved into: Insulin receptor subunit alpha; Insulin receptor subunit beta]
Gene: INSR

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.50	0.437

Property	Details
Experiments	35384245
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 308 Hs			1 1382
+	Rn
		102548 G3V8Q1_RAT (1-308): 5.75e-152: 428: 85.71		INSR_RAT (1-1382): 0: 1527: 94.44
+	Hs
		149554 COPE_HUMAN (1-308): 6.83e-167: 467: 100.00		EPHB2_HUMAN (521-1316): 3.12e-175: 551: 20.21
+	Hs
		149642 COPE_HUMAN (1-308): 6.83e-167: 467: 100.00		EPHA7_HUMAN (562-1356): 4.76e-172: 541: 19.48
+	Hs
		149553 COPE_HUMAN (1-308): 6.83e-167: 467: 100.00		EPHA8_HUMAN (644-1322): 3.66e-168: 531: 20.68
+	Hs
		149529 COPE_HUMAN (1-308): 6.83e-167: 467: 100.00		ROS1_HUMAN (511-1377): 3.38e-158: 530: 22.63
+	Hs
		149776 COPE_HUMAN (1-308): 6.83e-167: 467: 100.00		ALK_HUMAN (982-1339): 1.96e-70: 263: 40.53
+	Hs
		149486 COPE_HUMAN (1-308): 6.83e-167: 467: 100.00		MUSK_HUMAN (1017-1291): 1.24e-69: 254: 42.22
+	Hs
		149521 COPE_HUMAN (1-308): 6.83e-167: 467: 100.00		NTRK1_HUMAN (996-1286): 9.16e-68: 247: 42.62
+	Hs
		149647 COPE_HUMAN (1-308): 6.83e-167: 467: 100.00		NTRK3_HUMAN (996-1290): 1.93e-64: 238: 39.43