HitPredict

Interactor 1: COPE (O14579)
Coatomer subunit epsilon (Epsilon-coat protein) (Epsilon-COP)
Gene: COPE

Interactor 2: ROS1 (P08922)
Proto-oncogene tyrosine-protein kinase ROS (EC 2.7.10.1) (Proto-oncogene c-Ros) (Proto-oncogene c-Ros-1) (Receptor tyrosine kinase c-ros oncogene 1) (c-Ros receptor tyrosine kinase)
Gene: ROS1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.50	0.457

Property	Details
Experiments	35384245
Identification Methods	affinity chromatography technology
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 308 Hs			1 2347
+	Hs
		149554 COPE_HUMAN (1-308): 6.83e-167: 467: 100.00		EPHB2_HUMAN (1381-2344): 0: 601: 18.74
+	Hs
		149642 COPE_HUMAN (1-308): 6.83e-167: 467: 100.00		EPHA7_HUMAN (1385-2313): 1.98e-180: 581: 18.43
+	Hs
		149553 COPE_HUMAN (1-308): 6.83e-167: 467: 100.00		EPHA8_HUMAN (1383-2242): 1.9e-173: 562: 18.61
+	Hs
		149524 COPE_HUMAN (1-308): 6.83e-167: 467: 100.00		INSR_HUMAN (1424-2308): 7.33e-167: 555: 23.13
+	Rn
		102548 G3V8Q1_RAT (1-308): 5.75e-152: 428: 85.71		INSR_RAT (1424-2308): 1.37e-164: 549: 23.18
+	Hs
		149776 COPE_HUMAN (1-308): 6.83e-167: 467: 100.00		ALK_HUMAN (1858-2311): 4.31e-84: 309: 38.96