Interactor 1: COPE (O14579)
Coatomer subunit epsilon (Epsilon-coat protein) (Epsilon-COP)
Gene: COPE
Interactor 2: COPA (P53621)
Coatomer subunit alpha (Alpha-coat protein) (Alpha-COP) (HEP-COP) (HEPCOP) [Cleaved into: Xenin (Xenopsin-related peptide); Proxenin]
Gene: COPA
Species: Homo sapiens
Source: intact
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.94 | 1.00 | 0.972 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 27684187, 31712447, 16169070, 33961781, 35271311, 9482852, 10921873, 8858162, 9751720 |
| Identification Methods | affinity chromatography technology, x-ray crystallography, two hybrid, pull down, anti tag coimmunoprecipitation, two hybrid pooling approach |
| Interaction Type | physical association, association, direct interaction |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | COPI_C~Coatomer_E |
| Common GO terms | GO:0000139 - Golgi membrane GO:0005198 - structural molecule activity GO:0005789 - endoplasmic reticulum membrane GO:0005829 - cytosol GO:0006888 - endoplasmic reticulum to Golgi vesicle-mediated transport and 4 others more... |
| Homologous interactions | 8 |
Homologous interactions
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
