Interactor 1: CTDS2 (O14595)
Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 2 (EC 3.1.3.16) (Nuclear LIM interactor-interacting factor 2) (NLI-interacting factor 2) (Protein OS-4) (Small C-terminal domain phosphatase 2) (Small CTD phosphatase 2) (SCP2)
Gene: CTDSP2

Interactor 2: CTDSL (O15194)
CTD small phosphatase-like protein (CTDSP-like) (EC 3.1.3.16) (Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 3) (NIF-like protein) (Nuclear LIM interactor-interacting factor 1) (NLI-interacting factor 1) (Protein YA22) (hYA22) (RBSP3) (Small C-terminal domain phosphatase 3) (SCP3) (Small CTD phosphatase 3)
Gene: CTDSPL

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.47 1.00 0.691

The method score is based on:

Property Details
Experiments 33961781
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains NIF~NIF
Common GO terms GO:0001933 - negative regulation of protein phosphorylation
GO:0008420 - RNA polymerase II CTD heptapeptide repeat phosphatase activity
GO:0017018 - myosin phosphatase activity
GO:0046872 - metal ion binding
GO:2000134 - negative regulation of G1/S transition of mitotic cell cycle
Homologous interactions 7

Homologous interactions

Color coding for hit scores

1 271
Hs

1 276
+ Hs
+ Hs
+ Hs
+ Sc
+ Hs
+ Sc
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024