HitPredict

Interactor 1: BORG1 (O14613)
Cdc42 effector protein 2 (Binder of Rho GTPases 1)
Gene: CDC42EP2

Interactor 2: CDC42 (P60953)
Cell division control protein 42 homolog (EC 3.6.5.2) (G25K GTP-binding protein)
Gene: CDC42

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.95 1.00 0.975

The method score is based on:

Property Details
Experiments 10490598, 25416956, 32296183, 31478661, 11035016, 31871319, 20936779, 21988832, unassigned1304
Identification Methods pull down, two hybrid, affinity chromatography technology, validated two hybrid, two hybrid prey pooling approach, two hybrid array, two hybrid pooling approach
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains PBD~Ras
Common GO terms GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0005886 - plasma membrane
GO:0007015 - actin filament organization
GO:0016020 - membrane
and 4 others

more...
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 210
Hs

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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024