HitPredict

Interactor 1: AP3D1 (O14617)
AP-3 complex subunit delta-1 (AP-3 complex subunit delta) (Adaptor-related protein complex 3 subunit delta-1) (Delta-adaptin)
Gene: AP3D1

Interactor 2: NTRK1 (P04629)
High affinity nerve growth factor receptor (EC 2.7.10.1) (Neurotrophic tyrosine kinase receptor type 1) (TRK1-transforming tyrosine kinase protein) (Tropomyosin-related kinase A) (Tyrosine kinase receptor) (Tyrosine kinase receptor A) (Trk-A) (gp140trk) (p140-TrkA)
Gene: NTRK1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	25921289
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005769 - early endosome GO:0010008 - endosome membrane
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 1153 Hs			1 796
+	Hs
		119906 AP3B1_HUMAN (41-1152): 0: 664: 12.09		NTRK1_HUMAN (1-796): 0: 621: 100.00
+	Hs
		384781 AP3B2_HUMAN (41-1152): 0: 633: 12.59		NTRK1_HUMAN (1-796): 0: 621: 100.00
+	Hs
		212583 AP1G1_HUMAN (17-836): 0: 595: 18.83		NTRK1_HUMAN (1-796): 0: 621: 100.00
+	Hs
		384621 AP2B1_HUMAN (37-965): 0: 580: 14.83		NTRK1_HUMAN (1-796): 0: 621: 100.00
+	Hs
		384728 AP1B1_HUMAN (37-965): 0: 578: 15.09		NTRK1_HUMAN (1-796): 0: 621: 100.00
+	Hs
		385808 COPG1_HUMAN (32-869): 5.38e-174: 536: 12.63		NTRK1_HUMAN (1-796): 0: 621: 100.00
+	Hs
		385654 COPG2_HUMAN (32-869): 1.56e-172: 532: 12.76		NTRK1_HUMAN (1-796): 0: 621: 100.00
+	Hs
		507940 AP2B1_HUMAN (37-965): 0: 580: 14.83		FGFR1_HUMAN (195-794): 0: 545: 26.34
+	Hs
		1014018 AP1B1_HUMAN (37-965): 0: 578: 15.09		NTRK2_HUMAN (12-796): 1.28e-176: 529: 46.72
+	Hs
		302086 AP2A2_HUMAN (16-652): 7.04e-149: 472: 19.68		NTRK1_HUMAN (1-796): 0: 621: 100.00
+	Hs
		321460 AP2A1_HUMAN (16-729): 3.6e-148: 471: 18.78		NTRK1_HUMAN (1-796): 0: 621: 100.00
+	Hs
		508297 COPG1_HUMAN (32-869): 5.38e-174: 536: 12.63		FGFR1_HUMAN (195-794): 0: 545: 26.34
+	Hs
		321475 AP2A1_HUMAN (16-729): 3.6e-148: 471: 18.78		FGFR1_HUMAN (195-794): 0: 545: 26.34
+	Hs
		321487 AP2A1_HUMAN (16-729): 3.6e-148: 471: 18.78		FGFR3_HUMAN (168-794): 3.98e-158: 481: 25.98
+	Rn
		71352 B2RYN6_RAT (17-836): 0: 598: 18.71		INSR_RAT (493-777): 7.31e-66: 241: 41.95
+	Rn
		102587 G3V9N8_RAT (37-907): 1.57e-180: 555: 15.32		INSR_RAT (493-777): 7.31e-66: 241: 41.95
+	Rn
		544838 COPG1_RAT (32-869): 7.24e-172: 531: 12.98		INSR_RAT (493-777): 7.31e-66: 241: 41.95
+	At
		1352915 COPB2_ARATH (41-498): 7.15e-15: 81.6: 24.01		BRL2_ARATH (140-396): 2.09e-17: 89.3: 10.49