HitPredict

Interactor 1: AP3D1 (O14617)
AP-3 complex subunit delta-1 (AP-3 complex subunit delta) (Adaptor-related protein complex 3 subunit delta-1) (Delta-adaptin)
Gene: AP3D1

Interactor 2: CFTR (P13569)
Cystic fibrosis transmembrane conductance regulator (CFTR) (ATP-binding cassette sub-family C member 7) (Channel conductance-controlling ATPase) (EC 5.6.1.6) (cAMP-dependent chloride channel)
Gene: CFTR

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	31324722
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005765 - lysosomal membrane GO:0005769 - early endosome GO:0010008 - endosome membrane GO:0016020 - membrane
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 1153 Hs			1 1480
+	Hs
		528937 AP2B1_HUMAN (37-965): 0: 580: 14.83		CFTR_HUMAN (1-1480): 0: 1031: 100.00
+	Hs
		529041 AP1B1_HUMAN (37-965): 0: 578: 15.09		CFTR_HUMAN (1-1480): 0: 1031: 100.00
+	Hs
		529973 COPG1_HUMAN (32-869): 5.38e-174: 536: 12.63		CFTR_HUMAN (1-1480): 0: 1031: 100.00
+	Hs
		529843 COPG2_HUMAN (32-869): 1.56e-172: 532: 12.76		CFTR_HUMAN (1-1480): 0: 1031: 100.00
+	Hs
		321478 AP2A1_HUMAN (16-729): 3.6e-148: 471: 18.78		CFTR_HUMAN (1-1480): 0: 1031: 100.00