HitPredict

Interactor 1: AP3D1 (O14617)
AP-3 complex subunit delta-1 (AP-3 complex subunit delta) (Adaptor-related protein complex 3 subunit delta-1) (Delta-adaptin)
Gene: AP3D1

Interactor 2: FLT3 (P36888)
Receptor-type tyrosine-protein kinase FLT3 (EC 2.7.10.1) (FL cytokine receptor) (Fetal liver kinase-2) (FLK-2) (Fms-like tyrosine kinase 3) (FLT-3) (Stem cell tyrosine kinase 1) (STK-1) (CD antigen CD135)
Gene: FLT3

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	35384245
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0010008 - endosome membrane
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 1153 Hs			1 993
+	Hs
		150171 AP3D1_HUMAN (1-1153): 0: 917: 100.00		VGFR1_HUMAN (74-537): 1.47e-36: 152: 14.31
+	Hs
		119918 AP3B1_HUMAN (41-1152): 0: 664: 12.09		VGFR1_HUMAN (74-537): 1.47e-36: 152: 14.31
+	Hs
		507940 AP2B1_HUMAN (37-965): 0: 580: 14.83		FGFR1_HUMAN (6-360): 2.83e-24: 111: 10.90
+	Hs
		729398 COPG1_HUMAN (32-869): 5.38e-174: 536: 12.63		VGFR3_HUMAN (70-533): 8.45e-27: 120: 14.15
+	Hs
		729373 COPG2_HUMAN (32-869): 1.56e-172: 532: 12.76		VGFR3_HUMAN (70-533): 8.45e-27: 120: 14.15
+	Hs
		508297 COPG1_HUMAN (32-869): 5.38e-174: 536: 12.63		FGFR1_HUMAN (6-360): 2.83e-24: 111: 10.90
+	Hs
		321475 AP2A1_HUMAN (16-729): 3.6e-148: 471: 18.78		FGFR1_HUMAN (6-360): 2.83e-24: 111: 10.90
+	Hs
		321487 AP2A1_HUMAN (16-729): 3.6e-148: 471: 18.78		FGFR3_HUMAN (20-260): 5.2e-21: 101: 9.09