HitPredict

Interactor 1: AP3D1 (O14617)
AP-3 complex subunit delta-1 (AP-3 complex subunit delta) (Adaptor-related protein complex 3 subunit delta-1) (Delta-adaptin)
Gene: AP3D1

Interactor 2: ARRB1 (P49407)
Beta-arrestin-1 (Arrestin beta-1) (Non-visual arrestin-2)
Gene: ARRB1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	17620599
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000139 - Golgi membrane GO:0005765 - lysosomal membrane GO:0045944 - positive regulation of transcription by RNA polymerase II
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 1153 Hs			1 418
+	Hs
		150178 AP3D1_HUMAN (1-1153): 0: 917: 100.00		ARRB2_HUMAN (1-407): 0: 626: 76.15
+	Hs
		119935 AP3B1_HUMAN (41-1152): 0: 664: 12.09		ARRB1_HUMAN (1-418): 0: 716: 100.00
+	Hs
		827157 AP2B1_HUMAN (37-965): 0: 580: 14.83		ARRB1_HUMAN (1-418): 0: 716: 100.00
+	Hs
		119923 AP3B1_HUMAN (41-1152): 0: 664: 12.09		ARRB2_HUMAN (1-407): 0: 626: 76.15
+	Hs
		685933 AP3B2_HUMAN (41-1152): 0: 633: 12.59		ARRB2_HUMAN (1-407): 0: 626: 76.15
+	Hs
		685891 AP2B1_HUMAN (37-965): 0: 580: 14.83		ARRB2_HUMAN (1-407): 0: 626: 76.15
+	Hs
		685925 AP1B1_HUMAN (37-965): 0: 578: 15.09		ARRB2_HUMAN (1-407): 0: 626: 76.15
+	Rn
		663951 AP2B1_RAT (37-965): 0: 580: 14.83		ARRB2_RAT (1-407): 0: 616: 75.00
+	Hs
		321510 AP2A1_HUMAN (16-729): 3.6e-148: 471: 18.78		ARRB1_HUMAN (1-418): 0: 716: 100.00
+	Hs
		302104 AP2A2_HUMAN (16-652): 7.04e-149: 472: 19.68		ARRB2_HUMAN (1-407): 0: 626: 76.15
+	Hs
		321494 AP2A1_HUMAN (16-729): 3.6e-148: 471: 18.78		ARRB2_HUMAN (1-407): 0: 626: 76.15