Interactor 1: CCS (O14618)
Copper chaperone for superoxide dismutase (Superoxide dismutase copper chaperone)
Gene: CCS

Interactor 2: SODC (P00441)
Superoxide dismutase [Cu-Zn] (EC 1.15.1.1) (Superoxide dismutase 1) (hSod1)
Gene: SOD1

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.95 1.00 0.976

The method score is based on:

Property Details
Experiments 26496610, 28514442, 30735496, 33961781, 20154138, 9726962, 22508683, 24981860, 12968035
Identification Methods affinity chromatography technology, x-ray crystallography, pull down, anti tag coimmunoprecipitation, tandem affinity purification
Interaction Type physical association, association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains HMA~Sod_Cu, Sod_Cu~Sod_Cu
Common GO terms GO:0005507 - copper ion binding
GO:0005634 - nucleus
GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0006801 - superoxide metabolic process
and 1 others

more...

Homologous interactions 12

Homologous interactions

Color coding for hit scores

1 274
Hs

1 154
+ Hs
+ Hs
+ Dm
+ At
+ Hs
+ Sc
+ Mm
+ Sc
+ At
+ Bs
+ Se
+ Vv

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024