HitPredict

Interactor 1: CXL11 (O14625)
C-X-C motif chemokine 11 (Beta-R1) (H174) (Interferon gamma-inducible protein 9) (IP-9) (Interferon-inducible T-cell alpha chemoattractant) (I-TAC) (Small-inducible cytokine B11)
Gene: CXCL11

Interactor 2: DPP4 (P27487)
Dipeptidyl peptidase 4 (EC 3.4.14.5) (ADABP) (Adenosine deaminase complexing protein 2) (ADCP-2) (Dipeptidyl peptidase IV) (DPP IV) (T-cell activation antigen CD26) (TP103) (CD antigen CD26) [Cleaved into: Dipeptidyl peptidase 4 membrane form (Dipeptidyl peptidase IV membrane form); Dipeptidyl peptidase 4 soluble form (Dipeptidyl peptidase IV soluble form)]
Gene: DPP4

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.60	0.60	0.602

Property	Details
Experiments	18275857, 21314817
Identification Methods	enzymatic study, protease assay
Interaction Type	direct interaction, cleavage reaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005576 - extracellular region
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 94 Hs			1 766
+	Hs
		364101 CXL10_HUMAN (1-93): 5.22e-27: 96.3: 31.18		DPP4_HUMAN (1-766): 0: 862: 100.00
+	Hs
		587768 CXCL2_HUMAN (19-91): 1.84e-22: 85.1: 31.51		DPP4_HUMAN (1-766): 0: 862: 100.00
+	Hs
		648737 CXCL9_HUMAN (20-90): 3.13e-20: 80.1: 40.85		DPP4_HUMAN (1-766): 0: 862: 100.00
+	Hs
		648685 SDF1_HUMAN (1-94): 9.95e-20: 77.8: 25.53		DPP4_HUMAN (1-766): 0: 862: 100.00
+	Hs
		150330 CXL11_HUMAN (1-94): 1.5e-27: 97.8: 100.00		DPP8_HUMAN (79-764): 1.63e-169: 513: 22.21
+	Hs
		364116 CXL10_HUMAN (1-93): 5.22e-27: 96.3: 31.18		DPP8_HUMAN (79-764): 1.63e-169: 513: 22.21
+	Hs
		816318 SDF1_HUMAN (1-94): 9.95e-20: 77.8: 25.53		DPP8_HUMAN (79-764): 1.63e-169: 513: 22.21