HitPredict

Interactor 1: DVL1 (O14640)
Segment polarity protein dishevelled homolog DVL-1 (Dishevelled-1) (DSH homolog 1)
Gene: DVL1

Interactor 2: DVL2 (O14641)
Segment polarity protein dishevelled homolog DVL-2 (Dishevelled-2) (DSH homolog 2)
Gene: DVL2

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.90 1.00 0.954

The method score is based on:

Property Details
Experiments 31340145, 36398662, 26186194, 28514442, 33961781, 24643799, 20224554
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation, anti bait coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains DEP~DEP, DIX~DIX, PDZ~PDZ
Common GO terms GO:0001934 - positive regulation of protein phosphorylation
GO:0001947 - heart looping
GO:0003151 - outflow tract morphogenesis
GO:0005109 - frizzled binding
GO:0005829 - cytosol
and 14 others

more...
Homologous interactions 14

Homologous interactions

Color coding for hit scores

1 695
Hs

1 736
+ Mm
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024