HitPredict

Interactor 1: DVL1 (O14640)
Segment polarity protein dishevelled homolog DVL-1 (Dishevelled-1) (DSH homolog 1)
Gene: DVL1

Interactor 2: TLE2 (Q04725)
Transducin-like enhancer protein 2 (Enhancer of split groucho-like protein 2) (ESG2)
Gene: TLE2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.80	0.553

Property	Details
Experiments	37689310
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	DEP~WD40
Common GO terms	-
Homologous interactions	13

Homologous interactions

Color coding for hit scores

	1 695 Hs			1 743
+	Hs
		993528 DVL3_HUMAN (1-695): 1.01e-153: 463: 61.00		TLE5_HUMAN (1-185): 8.53e-92: 286: 62.89
+	Hs
		150960 DVL2_HUMAN (3-695): 1.59e-140: 430: 55.84		TLE5_HUMAN (1-185): 8.53e-92: 286: 62.89
+	Hs
		150744 DVL1_HUMAN (1-695): 0: 550: 100.00		SNR40_HUMAN (509-740): 1.7e-14: 77.8: 24.28
+	Hs
		150691 DVL1_HUMAN (1-695): 0: 550: 100.00		GBB2_HUMAN (659-742): 3.82e-14: 76.4: 17.65
+	Dm
		844368 DSH_DROME (2-547): 2.69e-107: 340: 44.84		EBI_DROME (211-703): 1.09e-81: 276: 11.33
+	Mm
		921807 NEB2_MOUSE (75-423): 2.88e-48: 184: 15.62		GNB5_MOUSE (438-739): 2.15e-87: 282: 20.70
+	Hs
		876342 AFAD_HUMAN (246-658): 1.91e-82: 288: 20.83		WDR5_HUMAN (628-742): 1.63e-35: 139: 21.37
+	Mm
		666791 DLG4_MOUSE (104-626): 5.62e-57: 208: 17.60		GBB4_MOUSE (484-742): 1.11e-45: 168: 17.91
+	Hs
		921015 INADL_HUMAN (249-359): 2.73e-12: 72.6: 27.03		GBB1_HUMAN (447-739): 3.21e-91: 290: 18.87
+	Mm
		921094 DLG4_MOUSE (104-626): 5.62e-57: 208: 17.60		GBB1_MOUSE (659-742): 7.85e-14: 75.5: 18.82
+	Mm
		921096 NEB2_MOUSE (75-423): 2.88e-48: 184: 15.62		GBB1_MOUSE (659-742): 7.85e-14: 75.5: 18.82
+	Hs
		1246436 INADL_HUMAN (249-359): 2.73e-12: 72.6: 27.03		GBB4_HUMAN (368-617): 7.53e-41: 154: 18.18
+	Hs
		921542 PTN13_HUMAN (68-520): 1.49e-10: 67.2: 13.25		GBB2_HUMAN (659-742): 3.82e-14: 76.4: 17.65