Interactor 1: DVL1 (O14640)
Segment polarity protein dishevelled homolog DVL-1 (Dishevelled-1) (DSH homolog 1)
Gene: DVL1

Interactor 2: LRRK2 (Q5S007)
Leucine-rich repeat serine/threonine-protein kinase 2 (EC 2.7.11.1) (EC 3.6.5.-) (Dardarin)
Gene: LRRK2

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.54 0.60 0.573

The method score is based on:

Property Details
Experiments 19625296
Identification Methods two hybrid, affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0001933 - negative regulation of protein phosphorylation
GO:0001934 - positive regulation of protein phosphorylation
GO:0005829 - cytosol
GO:0007528 - neuromuscular junction development
GO:0030426 - growth cone
and 10 others

more...

Homologous interactions 9

Homologous interactions

Color coding for hit scores

1 695
Hs

1 2527
+ Hs
+ Hs
+ Mm
+ Mm
+ Hs
+ Hs
+ Ce
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024