HitPredict

Interactor 1: DVL1 (O14640)
Segment polarity protein dishevelled homolog DVL-1 (Dishevelled-1) (DSH homolog 1)
Gene: DVL1

Interactor 2: DVL3 (Q92997)
Segment polarity protein dishevelled homolog DVL-3 (Dishevelled-3) (DSH homolog 3)
Gene: DVL3

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.68 1.00 0.828

The method score is based on:

Property Details
Experiments 32296183, 10330181
Identification Methods two hybrid, affinity chromatography technology, pull down, anti tag coimmunoprecipitation
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains DEP~DEP, DIX~DIX, PDZ~PDZ
Common GO terms GO:0001934 - positive regulation of protein phosphorylation
GO:0005109 - frizzled binding
GO:0005829 - cytosol
GO:0008013 - beta-catenin binding
GO:0031267 - small GTPase binding
and 9 others

more...
Homologous interactions 15

Homologous interactions

Color coding for hit scores

1 695
Hs

1 716
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024