Interactor 1: DVL2 (O14641)
Segment polarity protein dishevelled homolog DVL-2 (Dishevelled-2) (DSH homolog 2)
Gene: DVL2

Interactor 2: DVL2 (O14641)
Segment polarity protein dishevelled homolog DVL-2 (Dishevelled-2) (DSH homolog 2)
Gene: DVL2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.79 1.00 0.894

The method score is based on:

Property Details
Experiments 16189514, 27107012, 36398662
Identification Methods two hybrid, affinity chromatography technology, pull down, barcode fusion genetics two hybrid, validated two hybrid, two hybrid pooling approach
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains DEP~DEP, DIX~DIX, PDZ~PDZ
Common GO terms GO:0001843 - neural tube closure
GO:0001934 - positive regulation of protein phosphorylation
GO:0001947 - heart looping
GO:0003151 - outflow tract morphogenesis
GO:0005109 - frizzled binding
and 32 others

more...

Homologous interactions 14

Homologous interactions

Color coding for hit scores

1 736
Hs

1 736
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024