HitPredict

Interactor 1: DVL2 (O14641)
Segment polarity protein dishevelled homolog DVL-2 (Dishevelled-2) (DSH homolog 2)
Gene: DVL2

Interactor 2: P53 (P04637)
Cellular tumor antigen p53 (Antigen NY-CO-13) (Phosphoprotein p53) (Tumor suppressor p53)
Gene: TP53

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.82	0.60	0.703

The method score is based on:

Property	Details
Experiments	16189514, 27107012, 16713569, 31515488
Identification Methods	two hybrid, two hybrid array, barcode fusion genetics two hybrid, validated two hybrid, two hybrid pooling approach
Interaction Type	direct interaction, physical association

The annotation score is based on:

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0006355 - regulation of DNA-templated transcription and 2 others more... GO:0008104 - protein localization GO:0045944 - positive regulation of transcription by RNA polymerase II
Homologous interactions	2

Homologous interactions

Color coding for hit scores

	1	736
Hs

1	393

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024