HitPredict

Interactor 1: DVL2 (O14641)
Segment polarity protein dishevelled homolog DVL-2 (Dishevelled-2) (DSH homolog 2)
Gene: DVL2

Interactor 2: HSP7C (P11142)
Heat shock cognate 71 kDa protein (EC 3.6.4.10) (Heat shock 70 kDa protein 8) (Heat shock protein family A member 8) (Lipopolysaccharide-associated protein 1) (LAP-1) (LPS-associated protein 1)
Gene: HSPA8

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	29568061, 34299191
Identification Methods	proximity labelling technology, affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0030674 - protein-macromolecule adaptor activity
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 736 Hs			1 646
+	Hs
		150879 DVL2_HUMAN (1-736): 0: 547: 100.00		HS71L_HUMAN (2-646): 0: 966: 82.48
+	Mm
		50521 DLG4_MOUSE (108-707): 2.57e-75: 259: 15.85		A1L347_MOUSE (2-646): 0: 968: 83.26
+	Mm
		926133 DLG4_MOUSE (108-707): 2.57e-75: 259: 15.85		HSP7C_MOUSE (1-646): 0: 967: 99.85
+	Mm
		565427 DLG4_MOUSE (108-707): 2.57e-75: 259: 15.85		HSP72_MOUSE (2-612): 0: 936: 87.77
+	Hs
		503764 AFAD_HUMAN (256-701): 1.96e-50: 193: 20.93		HSP7C_HUMAN (1-646): 0: 967: 100.00
+	Hs
		871517 AFAD_HUMAN (256-701): 1.96e-50: 193: 20.93		HSP72_HUMAN (2-646): 0: 940: 85.47
+	Hs
		871546 PTN13_HUMAN (97-531): 5.7e-17: 88: 15.40		HSP72_HUMAN (2-646): 0: 940: 85.47