HitPredict

Interactor 1: DVL2 (O14641)
Segment polarity protein dishevelled homolog DVL-2 (Dishevelled-2) (DSH homolog 2)
Gene: DVL2

Interactor 2: TTK (P33981)
Dual specificity protein kinase TTK (EC 2.7.12.1) (Phosphotyrosine picked threonine-protein kinase) (PYT)
Gene: TTK

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	36398662
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 736 Hs			1 857
+	Hs
		150982 DVL2_HUMAN (1-736): 0: 547: 100.00		KCC2D_HUMAN (519-856): 1.32e-113: 357: 22.95
+	Mm
		103564 DVL1_MOUSE (11-736): 5.49e-170: 506: 57.32		G5E884_MOUSE (239-800): 9.68e-119: 372: 18.04
+	Hs
		150707 DVL1_HUMAN (11-736): 7.51e-163: 488: 57.32		KS6A2_HUMAN (525-818): 6.21e-81: 277: 22.29
+	Rn
		404387 DLG4_RAT (108-707): 4.11e-75: 258: 15.53		KPCA_RAT (367-850): 2.24e-118: 376: 14.74
+	Hs
		566353 DLG4_HUMAN (108-707): 2.94e-75: 259: 15.53		KPCA_HUMAN (367-850): 2.8e-118: 375: 14.94
+	Mm
		1112939 DLG4_MOUSE (108-707): 2.57e-75: 259: 15.85		PAK6_MOUSE (184-798): 1.02e-117: 374: 17.49
+	Rn
		404390 DLG3_RAT (80-706): 4.53e-72: 253: 15.10		KPCA_RAT (367-850): 2.24e-118: 376: 14.74
+	Mm
		1143346 DLG4_MOUSE (108-707): 2.57e-75: 259: 15.85		KCC2D_MOUSE (519-856): 1.32e-113: 357: 22.95
+	Hs
		1021591 DLG1_HUMAN (94-707): 5.4e-83: 284: 15.92		KCC2A_HUMAN (525-856): 3.17e-95: 308: 22.13
+	Rn
		506740 DLG1_RAT (94-707): 2.78e-80: 277: 15.12		KCC2A_RAT (525-856): 5.71e-95: 308: 21.84
+	Mm
		1143553 DLG4_MOUSE (108-707): 2.57e-75: 259: 15.85		KS6A2_MOUSE (509-846): 3.69e-98: 324: 21.23
+	Hs
		166544 AFAD_HUMAN (256-701): 1.96e-50: 193: 20.93		DCLK1_HUMAN (261-856): 2.24e-119: 380: 16.87
+	Mm
		515234 DLG4_MOUSE (108-707): 2.57e-75: 259: 15.85		KCC2A_MOUSE (525-856): 5.71e-95: 308: 21.84
+	Hs
		1271040 DLG3_HUMAN (80-706): 1.51e-73: 256: 14.93		KCC2A_HUMAN (525-856): 3.17e-95: 308: 22.13
+	Hs
		1021498 DLG1_HUMAN (94-707): 5.4e-83: 284: 15.92		KS6A2_HUMAN (525-818): 6.21e-81: 277: 22.29
+	Rn
		506744 DLG3_RAT (80-706): 4.53e-72: 253: 15.10		KCC2A_RAT (525-856): 5.71e-95: 308: 21.84
+	Hs
		876512 AFAD_HUMAN (256-701): 1.96e-50: 193: 20.93		PAK6_HUMAN (184-798): 2.15e-115: 368: 17.83
+	Hs
		1039101 RIMS1_HUMAN (92-722): 9.64e-47: 181: 14.15		KCC2D_HUMAN (519-856): 1.32e-113: 357: 22.95
+	Hs
		942348 DLG4_HUMAN (108-707): 2.94e-75: 259: 15.53		KS6A1_HUMAN (477-790): 7.04e-77: 266: 21.96
+	Mm
		829606 DLG4_MOUSE (108-707): 2.57e-75: 259: 15.85		CDK5_MOUSE (525-790): 6.21e-20: 93.2: 27.70