HitPredict

Interactor 1: DVL2 (O14641)
Segment polarity protein dishevelled homolog DVL-2 (Dishevelled-2) (DSH homolog 2)
Gene: DVL2

Interactor 2: EPS15 (P42566)
Epidermal growth factor receptor substrate 15 (Protein Eps15) (Protein AF-1p)
Gene: EPS15

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	31340145, 36398662
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0016235 - aggresome GO:0042127 - regulation of cell population proliferation
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 736 Hs			1 896
+	Hs
		151007 DVL2_HUMAN (1-736): 0: 547: 100.00		ITSN1_HUMAN (2-520): 3.13e-38: 157: 14.61
+	Hs
		151028 DVL2_HUMAN (1-736): 0: 547: 100.00		FKB15_HUMAN (76-873): 1.31e-37: 154: 11.35
+	Hs
		150837 DVL2_HUMAN (1-736): 0: 547: 100.00		MYH7_HUMAN (256-608): 1.36e-14: 80.6: 11.14
+	Hs
		151236 DVL2_HUMAN (1-736): 0: 547: 100.00		EP15R_HUMAN (417-891): 5.86e-14: 78.3: 11.98
+	Hs
		787904 PTN13_HUMAN (97-531): 5.7e-17: 88: 15.40		EPS15_HUMAN (1-896): 5.15e-160: 493: 100.00
+	Hs
		1200039 RIMS1_HUMAN (92-722): 9.64e-47: 181: 14.15		MRCKB_HUMAN (223-886): 2.4e-41: 167: 12.72
+	Hs
		255248 RIMS1_HUMAN (92-722): 9.64e-47: 181: 14.15		LIPA3_HUMAN (222-883): 2.91e-31: 134: 12.39
+	Hs
		259649 RIMS1_HUMAN (92-722): 9.64e-47: 181: 14.15		LIPA2_HUMAN (210-884): 2.13e-31: 134: 11.53
+	Hs
		1200001 RIMS1_HUMAN (92-722): 9.64e-47: 181: 14.15		EHD1_HUMAN (17-102): 8.74e-16: 83.5: 33.72