HitPredict

Interactor 1: DVL2 (O14641)
Segment polarity protein dishevelled homolog DVL-2 (Dishevelled-2) (DSH homolog 2)
Gene: DVL2

Interactor 2: KCC2D (Q13557)
Calcium/calmodulin-dependent protein kinase type II subunit delta (CaM kinase II subunit delta) (CaMK-II subunit delta) (EC 2.7.11.17)
Gene: CAMK2D

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	29426014
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 736 Hs			1 499
+	Mm
		1143346 DLG4_MOUSE (108-707): 2.57e-75: 259: 15.85		KCC2D_MOUSE (1-499): 0: 606: 100.00
+	Hs
		1038993 RIMS1_HUMAN (92-722): 9.64e-47: 181: 14.15		KCC2G_HUMAN (1-478): 0: 646: 75.45
+	Hs
		1021591 DLG1_HUMAN (94-707): 5.4e-83: 284: 15.92		KCC2A_HUMAN (1-474): 0: 541: 87.37
+	Rn
		506740 DLG1_RAT (94-707): 2.78e-80: 277: 15.12		KCC2A_RAT (1-474): 0: 542: 87.58
+	Mm
		515234 DLG4_MOUSE (108-707): 2.57e-75: 259: 15.85		KCC2A_MOUSE (1-474): 0: 542: 87.58
+	Mm
		1131547 DLG4_MOUSE (108-707): 2.57e-75: 259: 15.85		Q5SVI3_MOUSE (1-478): 0: 540: 80.31
+	Hs
		1271040 DLG3_HUMAN (80-706): 1.51e-73: 256: 14.93		KCC2A_HUMAN (1-474): 0: 541: 87.37
+	Rn
		506744 DLG3_RAT (80-706): 4.53e-72: 253: 15.10		KCC2A_RAT (1-474): 0: 542: 87.58
+	Hs
		1039101 RIMS1_HUMAN (92-722): 9.64e-47: 181: 14.15		KCC2D_HUMAN (1-499): 0: 606: 100.00
+	Hs
		1200029 RIMS1_HUMAN (92-722): 9.64e-47: 181: 14.15		KCC2A_HUMAN (1-474): 0: 541: 87.37
+	Dm
		677687 DLG1_DROME (13-707): 2.23e-52: 198: 14.00		KCC2A_DROME (1-472): 1.19e-178: 513: 74.56
+	Mm
		251104 DLG1_MOUSE (94-707): 3.76e-84: 287: 15.74		CSKP_MOUSE (10-308): 1.58e-88: 292: 47.71
+	Hs
		159200 DLG1_HUMAN (94-707): 5.4e-83: 284: 15.92		CSKP_HUMAN (10-308): 1.58e-88: 292: 47.71
+	Rn
		1144009 DLG1_RAT (94-707): 2.78e-80: 277: 15.12		CSKP_RAT (10-308): 1.2e-88: 292: 47.71
+	Hs
		159190 DLG4_HUMAN (108-707): 2.94e-75: 259: 15.53		CSKP_HUMAN (10-308): 1.58e-88: 292: 47.71
+	Hs
		159249 DLG3_HUMAN (80-706): 1.51e-73: 256: 14.93		CSKP_HUMAN (10-308): 1.58e-88: 292: 47.71
+	Mm
		659457 DLG4_MOUSE (108-707): 2.57e-75: 259: 15.85		KCC2B_MOUSE (321-478): 1.32e-51: 185: 79.75
+	Hs
		1038896 RIMS1_HUMAN (92-722): 9.64e-47: 181: 14.15		KCC2B_HUMAN (228-478): 1.5e-64: 223: 50.20