HitPredict

Interactor 1: DVL2 (O14641)
Segment polarity protein dishevelled homolog DVL-2 (Dishevelled-2) (DSH homolog 2)
Gene: DVL2

Interactor 2: AAK1 (Q2M2I8)
AP2-associated protein kinase 1 (EC 2.7.11.1) (Adaptor-associated kinase 1)
Gene: AAK1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	36398662
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 736 Hs			1 961
+	Hs
		1101669 DVL3_HUMAN (11-736): 4.58e-160: 482: 65.04		AAK1_HUMAN (1-961): 0: 720: 100.00
+	Hs
		151058 DVL2_HUMAN (1-736): 0: 547: 100.00		MARK2_HUMAN (6-739): 5.77e-127: 405: 15.61
+	Hs
		150862 DVL2_HUMAN (1-736): 0: 547: 100.00		MARK3_HUMAN (2-692): 2.26e-119: 383: 14.89
+	Hs
		151228 DVL2_HUMAN (1-736): 0: 547: 100.00		MARK1_HUMAN (4-739): 6.05e-119: 383: 17.11
+	Hs
		151042 DVL2_HUMAN (1-736): 0: 547: 100.00		NEK5_HUMAN (43-555): 3.42e-112: 363: 20.98
+	Xl
		844438 DVL2_XENLA (11-736): 4.16e-163: 490: 71.95		Q6DDZ8_XENLA (24-793): 1.96e-116: 388: 15.94
+	Mm
		949354 DLG1_MOUSE (94-707): 3.76e-84: 287: 15.74		TNIK_MOUSE (24-782): 6.51e-116: 388: 13.73
+	Mm
		251104 DLG1_MOUSE (94-707): 3.76e-84: 287: 15.74		CSKP_MOUSE (43-677): 4.34e-116: 379: 16.03
+	Hs
		159200 DLG1_HUMAN (94-707): 5.4e-83: 284: 15.92		CSKP_HUMAN (43-677): 4.25e-116: 379: 16.03
+	Mm
		1143531 DLG4_MOUSE (108-707): 2.57e-75: 259: 15.85		MINK1_MOUSE (23-896): 8.63e-120: 398: 15.18
+	Mm
		949302 DLG4_MOUSE (108-707): 2.57e-75: 259: 15.85		TNIK_MOUSE (24-782): 6.51e-116: 388: 13.73
+	Mm
		936174 DLG3_MOUSE (80-706): 1.04e-71: 252: 15.33		TNIK_MOUSE (24-782): 6.51e-116: 388: 13.73
+	Hs
		159190 DLG4_HUMAN (108-707): 2.94e-75: 259: 15.53		CSKP_HUMAN (43-677): 4.25e-116: 379: 16.03
+	Mm
		949394 DLG2_MOUSE (93-707): 2.89e-70: 248: 12.83		TNIK_MOUSE (24-782): 6.51e-116: 388: 13.73
+	Hs
		159249 DLG3_HUMAN (80-706): 1.51e-73: 256: 14.93		CSKP_HUMAN (43-677): 4.25e-116: 379: 16.03
+	Hs
		876427 AFAD_HUMAN (256-701): 1.96e-50: 193: 20.93		MARK2_HUMAN (6-739): 5.77e-127: 405: 15.61
+	Hs
		876440 AFAD_HUMAN (256-701): 1.96e-50: 193: 20.93		MINK1_HUMAN (23-889): 2.9e-117: 391: 15.13
+	Hs
		647852 AFAD_HUMAN (256-701): 1.96e-50: 193: 20.93		MARK3_HUMAN (2-692): 2.26e-119: 383: 14.89
+	Ce
		711481 Q18239_CAEEL (14-643): 2.24e-91: 303: 28.83		PLK1_CAEEL (52-328): 2.05e-15: 82.8: 30.35
+	Ce
		1093973 MIG5_CAEEL (12-558): 2.34e-78: 266: 25.85		PLK3_CAEEL (52-302): 8.94e-17: 87: 31.03