Interactor 1: DVL2 (O14641)
Segment polarity protein dishevelled homolog DVL-2 (Dishevelled-2) (DSH homolog 2)
Gene: DVL2

Interactor 2: LRRK2 (Q5S007)
Leucine-rich repeat serine/threonine-protein kinase 2 (EC 2.7.11.1) (EC 3.6.5.-) (Dardarin)
Gene: LRRK2

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.65 0.60 0.626

The method score is based on:

Property Details
Experiments 19625296, unassigned1853
Identification Methods two hybrid, affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type direct interaction, physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0001934 - positive regulation of protein phosphorylation
GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0008104 - protein localization
GO:0031267 - small GTPase binding
and 3 others

more...

Homologous interactions 8

Homologous interactions

Color coding for hit scores

1 736
Hs

1 2527
+ Hs
+ Hs
+ Mm
+ Mm
+ Hs
+ Ce
+ Hs
+ Hs

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Last updated: 15 Jul 2024