HitPredict

Interactor 1: DVL2 (O14641)
Segment polarity protein dishevelled homolog DVL-2 (Dishevelled-2) (DSH homolog 2)
Gene: DVL2

Interactor 2: CP135 (Q66GS9)
Centrosomal protein of 135 kDa (Cep135) (Centrosomal protein 4)
Gene: CEP135

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	26638075, 34079125
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	13

Homologous interactions

Color coding for hit scores

	1 736 Hs			1 1140
+	Hs
		150716 DVL1_HUMAN (11-736): 7.51e-163: 488: 57.32		CP135_HUMAN (1-1140): 1.31e-85: 303: 100.00
+	Hs
		1145869 DVL3_HUMAN (11-736): 4.58e-160: 482: 65.04		CP135_HUMAN (1-1140): 1.31e-85: 303: 100.00
+	Hs
		150999 DVL2_HUMAN (1-736): 0: 547: 100.00		EEA1_HUMAN (1-997): 1.2e-47: 188: 12.43
+	Hs
		150837 DVL2_HUMAN (1-736): 0: 547: 100.00		MYH7_HUMAN (588-1139): 1.75e-29: 129: 11.94
+	Hs
		1067454 DVL3_HUMAN (11-736): 4.58e-160: 482: 65.04		EEA1_HUMAN (1-997): 1.2e-47: 188: 12.43
+	Hs
		1113820 DVL3_HUMAN (11-736): 4.58e-160: 482: 65.04		GRDN_HUMAN (100-1138): 1.23e-43: 176: 11.61
+	Hs
		150759 DVL1_HUMAN (11-736): 7.51e-163: 488: 57.32		DAPLE_HUMAN (100-794): 4.47e-11: 69.7: 13.99
+	Hs
		876402 AFAD_HUMAN (256-701): 1.96e-50: 193: 20.93		GRDN_HUMAN (100-1138): 1.23e-43: 176: 11.61
+	Hs
		725194 RIMS1_HUMAN (92-722): 9.64e-47: 181: 14.15		MYH10_HUMAN (410-1140): 1.54e-40: 166: 13.95
+	Hs
		876522 AFAD_HUMAN (256-701): 1.96e-50: 193: 20.93		DAPLE_HUMAN (100-794): 4.47e-11: 69.7: 13.99
+	Hs
		724903 RIMS1_HUMAN (92-722): 9.64e-47: 181: 14.15		MYH9_HUMAN (2-429): 6.32e-14: 79: 11.93
+	Hs
		724845 DIXC1_HUMAN (14-89): 2.09e-29: 126: 43.42		MYH9_HUMAN (2-429): 6.32e-14: 79: 11.93
+	Hs
		280085 MPDZ_HUMAN (242-350): 1.97e-12: 73.4: 28.18		DAPLE_HUMAN (100-794): 4.47e-11: 69.7: 13.99