HitPredict

Interactor 1: DVL2 (O14641)
Segment polarity protein dishevelled homolog DVL-2 (Dishevelled-2) (DSH homolog 2)
Gene: DVL2

Interactor 2: A16L1 (Q676U5)
Autophagy-related protein 16-1 (APG16-like 1)
Gene: ATG16L1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.68	1.00	0.827

Property	Details
Experiments	29634390, 25825496, 34299191
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	DEP~WD40
Common GO terms	GO:0005829 - cytosol
Homologous interactions	13

Homologous interactions

Color coding for hit scores

	1 736 Hs			1 607
+	Hs
		150717 DVL1_HUMAN (11-736): 7.51e-163: 488: 57.32		A16L1_HUMAN (1-607): 3.73e-164: 483: 100.00
+	Hs
		150744 DVL1_HUMAN (11-736): 7.51e-163: 488: 57.32		SNR40_HUMAN (175-514): 5.61e-65: 218: 16.48
+	Hs
		150691 DVL1_HUMAN (11-736): 7.51e-163: 488: 57.32		GBB2_HUMAN (165-516): 9.92e-44: 161: 16.62
+	Hs
		1075487 DIXC1_HUMAN (14-89): 2.09e-29: 126: 43.42		A16L1_HUMAN (1-607): 3.73e-164: 483: 100.00
+	Dm
		844368 DSH_DROME (9-563): 1.78e-121: 379: 46.29		EBI_DROME (163-478): 2.44e-58: 209: 15.93
+	Hs
		1020178 PTN13_HUMAN (97-531): 5.7e-17: 88: 15.40		A16L1_HUMAN (1-607): 3.73e-164: 483: 100.00
+	Hs
		1146639 INADL_HUMAN (243-345): 1.2e-12: 73.8: 26.85		A16L1_HUMAN (1-607): 3.73e-164: 483: 100.00
+	Mm
		921094 DLG4_MOUSE (108-707): 2.57e-75: 259: 15.85		GBB1_MOUSE (165-516): 5.41e-43: 159: 17.18
+	Hs
		876342 AFAD_HUMAN (256-701): 1.96e-50: 193: 20.93		WDR5_HUMAN (183-393): 4.59e-20: 93.6: 13.45
+	Hs
		921542 PTN13_HUMAN (97-531): 5.7e-17: 88: 15.40		GBB2_HUMAN (165-516): 9.92e-44: 161: 16.62
+	Hs
		301487 RIMS1_HUMAN (92-722): 9.64e-47: 181: 14.15		WDR47_HUMAN (315-396): 1.12e-10: 66.7: 22.62
+	Hs
		921015 INADL_HUMAN (243-345): 1.2e-12: 73.8: 26.85		GBB1_HUMAN (165-516): 5.41e-43: 159: 17.18
+	Hs
		1246436 INADL_HUMAN (243-345): 1.2e-12: 73.8: 26.85		GBB4_HUMAN (165-516): 4.49e-42: 156: 16.07